Autologous Platelet-Rich Plasma Combined with Endometrial Microstimulation to Improve Thin Endometrium Status and Clinical Outcomes: A Prospective Controlled Study

Study Overview

This study looked at how injecting a patient’s own platelet-rich plasma (PRP) into the uterus affects women with thin endometrium who are trying to conceive using frozen embryos.

Methods

Seventy women with thin endometrium participated in this study. They were divided into two groups: one received a single PRP infusion, while the other group received PRP along with a treatment called endometrial microstimulation. The thickness of the endometrium was measured before and after the treatments, and various pregnancy outcomes were analyzed.

Results

Both treatment groups experienced a significant increase in endometrial thickness after the procedures. However, the group that received both treatments showed a greater improvement. While both groups had better endometrial health, there were no significant differences in pregnancy-related outcomes such as embryo implantation or miscarriage rates.

Conclusion

Both treatment options (PRP alone and PRP with microstimulation) effectively improved endometrial thickness in women with thin endometrium. The combination therapy may offer better results, indicating a need for further research.

Practical Healthcare Solutions

Clinics can use this study to:

  • Set clear goals for improving endometrial health in patients.
  • Measure outcomes such as endometrial thickness and pregnancy rates.
  • Consider implementing combined PRP and microstimulation treatments based on these findings.

AI Tools for Clinical Needs

To enhance patient care, clinics can choose AI solutions tailored to track treatment outcomes and patient progress effectively.

Implementation Steps

Start with a small pilot project using the study’s results, track the outcomes, and expand based on real-world effectiveness.

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