Clinical trials

“`html Dynamic changes in the gut microbiota after bismuth quadruple therapy and high-dose dual therapy for Helicobacter pylori eradication ABSTRACT A study compared the impact of high-dose dual therapy (HDDT) and bismuth quadruple therapy (BQT) on the gut microbiota of patients with Helicobacter pylori infection. Patients provided fecal samples at baseline, Week 2, and Week […] ➡️➡️➡️

“`html Study Summary: Determining Optimal Bupivacaine Dose for Cesarean Section at High Altitude At moderately high altitudes, the need for local anesthesia during cesarean sections can be different due to altitude-related changes. This study aimed to find the right dose of bupivacaine for spinal anesthesia during cesarean sections at moderately high altitudes. Methods and Findings […] ➡️➡️➡️

“`html A Comparative Study of Clinical Outcomes in Locally Advanced Cervical Cancer Key Findings: The study compared the outcomes of two treatment approaches for locally advanced cervical cancer in women. It focused on the use of external beam radiation therapy (EBRT) and sequential High Dose Rate Intracavitary Brachytherapy (HDRICBT) with or without concurrent cisplatin administration […] ➡️➡️➡️

“`html The Impact of Tumor Hypoxia Modulation on sIL-2R Levels in Newly Diagnosed Diffuse Large B Cell Lymphoma (DLBCL) Patients Undergoing Chemotherapy: A Randomized Clinical Trial Objective This study aimed to investigate the effect of tumor hypoxia modulation using carbogen and nicotinamide on reducing soluble interleukin-2 receptor (sIL-2R) levels in newly diagnosed DLBCL patients with […] ➡️➡️➡️

“`html Safety and Efficacy of Umbilical Cord Tissue-Derived Mesenchymal Stem Cells in Treating Aging Frailty Key Findings: • Intravenous infusion of human umbilical cord-derived MSCs (HUC-MSCs) showed significant improvements in quality of life and physical performance in patients with aging frailty. • The treatment also led to a reduction in chronic inflammation, indicating its potential […] ➡️➡️➡️

“`html The Impact of Mindfulness-Based Stress Reduction on Acute Central Serous Chorioretinopathy Understanding Mindfulness-Based Stress Reduction Mindfulness-Based Stress Reduction (MBSR) is a form of meditation that combines mindfulness techniques with elements of cognitive-behavioral therapy. It aims to increase awareness of thoughts, emotions, and physical sensations without judgment or reaction, and has been shown to reduce […] ➡️➡️➡️

“`html Enhancing Diagnosis of Benign Lesions and Lung Cancer through Ensemble Text and Breath Analysis: A Retrospective Cohort Study The Study Lung cancer is a leading cause of cancer-related deaths worldwide, and early detection and accurate diagnosis are critical for improving survival rates. The study aimed to evaluate the effectiveness of using ensemble text and […] ➡️➡️➡️

“`html The Impact of Rimegepant Orally Disintegrating Tablet 75 mg on Acute Migraine Treatment in Adults from China Understanding Rimegepant Rimegepant is a new medication designed to provide fast relief for acute migraine attacks. It works by blocking a protein called CGRP, which is believed to play a key role in migraine attacks. The orally […] ➡️➡️➡️

“`html The Relationship Between Serum Resolvin D1, NLRP3, Cytokine Levels, and Adolescents with First-Episode Medication-Naïve Major Depressive Disorder What are Resolvins? Resolvins are natural compounds produced by the body that help reduce inflammation and promote tissue repair. The Role of Resolvin D1 in Depression Individuals with depression have been found to have lower levels of […] ➡️➡️➡️

“`html Susceptibility to Stress and Nature Exposure: Unveiling Differential Susceptibility to Physical Environments The Study Design A randomized controlled trial was conducted with 100 participants to investigate the relationship between susceptibility to stress and nature exposure. Participants were assigned to either a nature exposure group or a control group. The nature exposure group spent at […] ➡️➡️➡️

“`html Deep Learning: A Game-Changer in Esophageal Cancer Detection The Need for Early Detection Esophageal cancer is one of the most deadly forms of cancer, often diagnosed at a late stage when treatment options are limited. A recent clinical trial has shown promising results in the early detection of esophageal cancer and precursor lesions using […] ➡️➡️➡️

“`html The ON-SCENE Study: A Breakthrough in Pre-Hospital Emergency Care What is the ON-SCENE Study? The ON-SCENE study is a groundbreaking national multi-centre pre-hospital ECPR (extracorporeal cardiopulmonary resuscitation) stepped wedge study. It aims to evaluate the effectiveness of ECPR in improving survival rates for patients who suffer from cardiac arrest outside of a hospital setting. […] ➡️➡️➡️

“`html The Importance of Adherence to Antidepressant Medication for Patients with Depressive Disorders Depression is a common mental health disorder affecting millions worldwide. Antidepressant medication is a commonly prescribed treatment, but many patients do not adhere to their regimen, leading to treatment failure and other serious consequences. The Clinical Trial: Design and Methodology The clinical […] ➡️➡️➡️

“`html The Impact of Ankle Kinesio Taping on Pain Management in Patients with Acute Ankle Sprain The Study Ankle sprains are common, affecting 25,000 people daily in the US. Ankle kinesio taping is widely used for treatment, but its effectiveness was uncertain. A study at the University of California, Irvine, with 60 participants sought to […] ➡️➡️➡️

“`html Incidence of Total Knee Arthroplasty After Arthroscopic Surgery for Knee Osteoarthritis: A Secondary Analysis of a Randomized Clinical Trial The Impact of Arthroscopic Surgery on Total Knee Arthroplasty Incidence in Patients with Knee Osteoarthritis Knee osteoarthritis (OA) is a common degenerative joint disease that affects millions of people worldwide, causing pain, stiffness, and reduced […] ➡️➡️➡️

“`html ICG-Fluorescence Imaging for Margin Assessment During Minimally Invasive Colorectal Liver Metastasis Resection The Importance of Margin Assessment in Colorectal Liver Metastasis Resection Colorectal cancer often leads to liver metastasis, and surgery is the best treatment. However, it’s hard to remove the tumor without harming healthy tissue. ICG-Fluorescence Imaging helps solve this problem. What is […] ➡️➡️➡️

“`html The TIFFANI Study: Tolerance Induction through Early Feeding to Prevent Food Allergy in Infants and Children The Rationale Behind the Study Food allergies affect a significant number of individuals and there is currently no cure. The TIFFANI study aims to explore the potential of early feeding to prevent food allergies in infants and children. […] ➡️➡️➡️

“`html The Importance of Family Management for Children with Epilepsy Epilepsy affects millions of people worldwide and can significantly impact a person’s quality of life. Managing epilepsy involves not only treating seizures but also addressing the emotional, social, and psychological aspects of the condition. Family management plays a crucial role in improving the overall well-being […] ➡️➡️➡️

“`html The Preterm Birth Screening Study: A Breakthrough in Identifying and Preventing Preterm Births The Need for Early Detection of Preterm Births Preterm birth, occurring before 37 weeks of gestation, is a significant global health concern leading to neonatal mortality and long-term health issues in children. The Preterm Birth Screening Study has presented promising results […] ➡️➡️➡️

“`html Feasibility and Acceptability of NIDUS-Professional: A Training and Support Intervention for Homecare Workers Caring for Clients Living with Dementia The Need for NIDUS-Professional Dementia affects millions worldwide, and as the population ages, the number of individuals living with dementia is expected to increase significantly. Homecare workers often lack the necessary training and support to […] ➡️➡️➡️