Clinical trials

Study Overview This clinical trial tested a gel made from copaiba oil to see if it could help with dental sensitivity and color changes after teeth whitening. Study Details Seventy-five volunteers participated in the study, divided into three groups: GC: Placebo gel (no active ingredients) GKF2%: Gel containing 5% potassium nitrate and 2% sodium fluoride […] ➡️➡️➡️

Feasibility and Potential Benefits of Moderate Intensity Cycling in People with Lower Limb Lymphedema Study Overview This study looked at how practical it is to use moderate intensity cycling as a treatment for people with lower limb lymphedema (LLL) and what benefits it might provide. It involved 33 participants who exercised at home for 8 […] ➡️➡️➡️

Study Overview This study examined the effectiveness and safety of a combination therapy using low-intensity atorvastatin (5 mg) and ezetimibe (10 mg) in patients with high cholesterol levels, compared to standard treatments. Study Details The research involved 252 patients with dyslipidemia across 25 centers in South Korea. Participants were divided into four groups receiving different […] ➡️➡️➡️

Introduction Pre-exposure prophylaxis (PrEP) services are associated with more diagnoses of sexually transmitted infections (STIs). This may encourage more people to start using PrEP. We wanted to see if testing and treating STIs right at the clinic could help more people begin and continue using PrEP. Study Overview From September 2023 to November 2024, we […] ➡️➡️➡️

Background Trauma injuries lead to about 4.4 million deaths each year worldwide. Not detecting bleeding in trauma patients can increase the risk of death. This study looks at how central capillary refill time (CRT) relates to mortality in adult trauma patients, especially those with normal heart rates and blood pressure. Methods This study analyzed data […] ➡️➡️➡️

Background Recent guidelines suggest using primary human papillomavirus (HPV) screening for cervical cancer. However, there is limited guidance on how to effectively implement this change in practice. This study compared two approaches: one that is centrally administered with local adjustments and another that is centrally administered with standard care. Methods This study was conducted within […] ➡️➡️➡️

Clinical Trial Summary: 10% Intravenous Immunoglobulin (IVIG) for ITP Study Overview A recent clinical trial tested a new 10% IVIG treatment for adults with persistent or chronic primary immune thrombocytopenia (ITP). This condition leads to low platelet counts, increasing bleeding risk. The study involved adult patients in China with very low platelet counts (below 30 […] ➡️➡️➡️

Study Overview This study looked at how practicing Tai Chi and Qigong for 13 weeks affects anxiety and stress in middle-aged and older Brazilian patients with diabetes and high blood pressure. Study Details Ninety-one patients were divided into two groups: one practiced Tai Chi/Qigong (45 patients), and the other waited (46 patients). We measured their […] ➡️➡️➡️

Understanding Burning Eye Syndrome (BES) Burning Eye Syndrome (BES) is a type of dry eye syndrome that causes pain and discomfort that doesn’t get better with usual treatments. This is because traditional treatments don’t effectively address the nerve issues involved in BES. Study Purpose The goal of this study was to test a new treatment […] ➡️➡️➡️

Overview of Electromagnetic Stimulation for Urinary Incontinence Electromagnetic stimulation (EMS) is a new treatment option for women dealing with urinary incontinence, especially after childbirth. This study looked at how effective EMS is compared to traditional Kegel exercises for improving symptoms of stress urinary incontinence (SUI). Study Details The study included postpartum women diagnosed with SUI […] ➡️➡️➡️

Overview of the Study This study focused on patients with acyanotic shunt congenital heart disease (CHD) who often develop pulmonary hypertension (PH) by adulthood. The goal was to see if cilostazol, a specific medication, could improve heart function and overall fitness in these patients. Study Design The research was conducted at Dr. Kariadi Hospital in […] ➡️➡️➡️

“`html Telemedicine for Drug-Induced Movement Disorders Background People taking certain medications may develop movement disorders. It’s crucial to identify and manage these issues early to prevent them from worsening. Neurologists can help doctors understand these disorders and suggest treatment options. This study explores using telemedicine to provide neurological consultations for patients with these disorders. Methods […] ➡️➡️➡️

Study Overview This study looked at how detailed testing of lung samples affects treatment for patients with community-acquired pneumonia (CAP). It involved 118 patients who were divided into two groups: one group received extensive testing (64 patients), while the other group received standard care (54 patients). Key Findings The main goal was to see if […] ➡️➡️➡️

Background Pregnant women facing social challenges, such as stress or mental health issues, may have higher stress hormone levels. This can negatively impact their baby’s brain development and the mother-child bond, leading to potential long-term health and social issues for the child. While parenting programs have shown promise, little evidence exists on their effectiveness in […] ➡️➡️➡️

Clinical Trial Summary: Lithium vs. Quetiapine for Treatment-Resistant Depression Background Treatment-resistant depression (TRD) can be challenging for patients and healthcare providers. Lithium and quetiapine are common medications used to enhance the effects of antidepressants. However, there has been limited research directly comparing these options, especially over longer periods. Trial Objectives This trial aimed to determine […] ➡️➡️➡️

Introduction The SELECT-MONOTHERAPY trial showed that upadacitinib (UPA) can be a safe and effective treatment for rheumatoid arthritis patients who didn’t respond well to methotrexate. This report highlights key findings from the 260-week follow-up. Study Overview In this study, patients were randomly assigned to continue methotrexate or switch to UPA at doses of 15 mg […] ➡️➡️➡️

Background Access to spirometry, a test for lung function, is often limited because traditional spirometers are expensive and not easy to use. This can make it hard to diagnose and manage chronic respiratory diseases like COPD and asthma. Portable spirometers could be a better option since they are cheaper, easier to use, and more convenient […] ➡️➡️➡️

Background New lung testing devices have been developed, and we need to check how reliable the MeHow MeAir 9000 spirometer is for measuring lung function. Objective The goal is to see how accurate the MeHow MeAir 9000 spirometer is in measuring lung diffusing capacity. Methods We studied 166 people: 30 healthy individuals, 68 with interstitial […] ➡️➡️➡️

Background The U-ACTIVATE study is looking at how effective and safe the medicine upadacitinib is for people with moderate to severe ulcerative colitis over a long time. This report shares findings after 3 years of treatment. Study Details This study is ongoing and will last 288 weeks. It involves 307 centers in 43 countries, starting […] ➡️➡️➡️

Background Insulin sensitivity is important for preventing metabolic diseases, especially in adults who survived childhood cancer. The APACIS study aims to explore how two different exercise programs can improve health and metabolism in children diagnosed with cancer. Study Methods The APACIS trial involves children diagnosed with any type of pediatric cancer. These children are randomly […] ➡️➡️➡️