Effect of Stannous Fluoride Toothpaste on Dentin Hypersensitivity
Background
Dentin hypersensitivity is a common dental issue worldwide. This study tested a special toothpaste containing 0.454% stannous fluoride, along with nitrate and phosphates, to see if it could help reduce this sensitivity.
Methods
We treated human dentin samples with different toothpaste mixtures and checked how well they blocked dentin. In a phase III clinical trial, participants were divided into three groups: one using the SNaP toothpaste, another using a potassium nitrate toothpaste, and a third using a non-desensitizing fluoride toothpaste. We assessed sensitivity at the beginning, and after 1, 3, and 7 days using touch and air blast tests.
Results
The in vitro results showed that the SNaP toothpaste blocked 86% of dentin tubules compared to only 35% for the control toothpaste. A total of 120 participants completed the trial. After 7 days, those using SNaP reported a significant drop in sensitivity compared to both control groups. The SNaP toothpaste provided relief from the first day and continued to improve with use.
Conclusions
The findings suggest that SNaP toothpaste effectively blocks exposed dentin and reduces sensitivity quickly.
Practical Implications
This toothpaste formula not only decreases dentin hypersensitivity but also enhances patients’ daily lives and oral health, potentially preventing more serious dental issues later on.
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