Effect of Postbiotic Bifidobacterium longum CECT 7347 on Digestive Health
Study Overview
This study evaluated the impact of heat-treated Bifidobacterium longum CECT 7347 (HT-ES1) on digestive symptoms in healthy adults. It was a randomised, double-blind, placebo-controlled trial with 60 participants over 8 weeks, followed by a check-in at week 10.
Key Methods
Researchers measured:
- Gastrointestinal symptoms using various scales
- Gut microbiome changes
- Biochemical markers and physical measurements
- Any adverse effects
Main Findings
The study found:
- Small changes in digestive symptoms overall
- A significant reduction in total and non-HDL cholesterol in the HT-ES1 group
- An increase in beneficial gut bacteria linked to butyrate production
- Stable levels of faecal calprotectin in the HT-ES1 group, while it increased in the placebo group
Conclusions
HT-ES1 may support gut health by:
- Boosting butyrate-producing bacteria
- Maintaining normal faecal calprotectin levels
- Lowering serum cholesterol
Clinical Implications
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