Conditions: Advanced Breast Cancer; ER-positive Breast Cancer; HER2-negative Breast Cancer; ESR1 Gene Mutation
Interventions: Drug: Everolimus; Drug: Elacestrant; Drug: Placebo; Drug: Auxiliary Medicinal Product – Dexamethasone; Drug: Auxiliary Medicinal Product – Luteinizing hormone-releasing hormone (LHRH) analogues
Sponsors: MedSIR; Stemline Therapeutics, Inc.
Not yet recruiting
Overview of the Study This study focused on breast cancer survivors who often face long-lasting symptoms such as anxiety, stress, insomnia, menopausal symptoms, and cognitive issues. The goal was to…
Embodied Cognition Driven Qigong: Managing Depression and Preventing Relapse in Substance Use Disorders Objective Substance use disorders (SUDs) are a major public health issue, with high relapse rates. This study…
Background Calcium and magnesium levels in the blood are important for blood clotting and may affect how brain bleeding (intracerebral hemorrhage or ICH) worsens. This study aimed to maintain specific…
Understanding the Terms of Use for AI-Driven Medical Solutions: A Guide from MedTech Experts By Dr. Maxwell Trenton, Head of AI Solutions at MedTech Innovators Ltd. Why Transparency Matters in…
“`html The Impact of Rimegepant Orally Disintegrating Tablet 75 mg on Acute Migraine Treatment in Adults from China Understanding Rimegepant Rimegepant is a new medication designed to provide fast relief…
Efficacy and Safety of Methotrexate Plus Hydroxychloroquine Combination Therapy vs. Methotrexate Monotherapy in the Treatment of Rheumatoid Arthritis: A Randomized Controlled Clinical Trial Key Findings: Combining methotrexate (MTX) with hydroxychloroquine…
Background Excess fat in the liver can lead to a condition called metabolic dysfunction-associated steatotic liver disease (MASLD). This study looked at how weight loss affects fat buildup in the…
Understanding Patient Reactions to AI and Clinician Discrepancies As the use of artificial intelligence (AI) in medical imaging grows, radiologists are starting to use AI to help detect lung cancer…
Study on Bowling Skills in Children with Autism Purpose The study aimed to compare two learning methods to improve bowling skills in children with autism spectrum disorder (ASD). Method Twenty…
Performance of Diagnostic Methods for Soil-Transmitted Helminth Infections Background The World Health Organization suggests using the Kato-Katz method, a simple and cost-effective test, to diagnose soil-transmitted helminth (STH) infections. However,…
Study Title: Sibling-Support for Adolescent Girls (SSAGE) Objective: Preventing Mental Illness among Forcibly Displaced Adolescent Girls Forcibly displaced adolescent girls are at higher risk for mental illness, especially due to…
Introducing MEGALODON: A Breakthrough in AI Sequence Modeling Solving the Challenge of Processing Long Text Data Efficiently handling long text data is crucial for natural language processing. Traditional Transformer models…
Background Cervical cancer is the most common cancer among women in Uganda, with many diagnosed at advanced stages. The best way to prevent this is through the Human Papillomavirus (HPV)…
Interpreter Communication Quality in Cognitive Assessments for Dementia The MINDSET Randomized Clinical Trial Importance: As dementia cases rise with an aging population, interpreters play a crucial role in helping doctors…
Anti-dsDNA IgE: a Potential Non-Invasive Test for Prediction of Lupus Nephritis Relapse RMD Open. 2024 Jun 28;10(2):e004255. doi: 10.1136/rmdopen-2024-004255. Objectives: The WIN-IgE study aims to assess the value of serum…
