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Endovascular thrombectomy in wake-up stroke guided by arterial spin-labeling and fluid-attenuated inversion recovery versus diffusion-weighted imaging mismatch on MRI

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Study Summary

The study aimed to investigate the effectiveness and safety of using a combination of imaging techniques in treating wake-up stroke (WUS) patients.

Methods

  • Patients with WUS and specific imaging characteristics underwent either endovascular thrombectomy plus medical therapy or medical therapy alone.
  • Functional outcomes were assessed using the modified Rankin scale (mRs) at 90 days.

Results

  • Endovascular therapy group showed better functional prognosis at 90 days and a higher proportion of patients achieving functional independence compared to the medical therapy group.
  • No significant differences were observed in the incidence of intracranial hemorrhage or mortality rates between the two groups.

Conclusion

Endovascular thrombectomy combined with standard medical treatment appears to yield superior functional outcomes in patients with WUS and large vessel occlusion compared to standard medical treatment alone.

Full Clinical Trial Report

Access the full report here

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