Etomidate Combined with Propofol versus Remimazolam for Sedation in Elderly Patients During Gastrointestinal Endoscopy: A Randomized Prospective Clinical Trial

Study Summary

Comparison of Sedation Drugs in Elderly Patients During Gastrointestinal Endoscopy

Researchers compared the use of remimazolam besylate and a combination of etomidate and propofol for sedation in elderly patients undergoing gastrointestinal endoscopy. The study aimed to assess the effectiveness and safety of these sedation methods.

Key Findings

Remimazolam besylate showed comparable safety and efficacy to the etomidate and propofol combination, making it a safe option for sedation during gastrointestinal endoscopy in elderly patients with ASA I-II. However, careful monitoring is necessary to address the occurrence of hiccups.

Practical Solutions and Value

Remimazolam besylate demonstrated a shorter post-anesthesia care unit (PACU) time and higher sedation satisfaction rate compared to the etomidate and propofol combination. It also resulted in a lower impact on patients’ lives within 24 hours post-procedure. These findings highlight the potential practical benefits of using remimazolam besylate for sedation in elderly patients during gastrointestinal endoscopy.

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