Evaluation and comparison of the effects of a new paste containing 8% L-Arginine and CaCO3 plus KNO3 on dentinal tubules occlusion and dental sensitivity: a randomized, triple blinded clinical trial study

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Evaluation and Comparison of a New Desensitizing Paste

Study Overview

A clinical trial studied the effects of a new paste containing 8% L-Arginine and CaCO3 plus KNO3 on dentinal tubules occlusion and dental sensitivity.

Methods

24 dentin surfaces were divided into two groups, one receiving the experimental paste and the other a placebo. Permeability and sealing ability were assessed, and the paste’s effects on hypersensitivity were examined in a clinical trial with 16 patients.

Results

The experimental group showed a significant reduction in dentin permeability and most dentinal tubules were occluded. Both groups demonstrated a decrease in sensitivity to various stimuli throughout the study.

Conclusion

The new desensitizing paste effectively occluded dentinal tubules, reduced dentin permeability, and mitigated dentin hypersensitivity to various stimuli.

TRIAL REGISTRATION: IRCT20220829055822N1

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