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Heat-sensitive moxibustion combined with tropisetron hydrochloride for chemotherapy-induced nausea and vomiting: a randomized controlled trial

Heat-sensitive moxibustion combined with tropisetron hydrochloride for chemotherapy-induced nausea and vomiting: a randomized controlled trial

Objective

To compare the effectiveness of heat-sensitive moxibustion combined with tropisetron hydrochloride versus tropisetron hydrochloride alone in treating chemotherapy-induced nausea and vomiting (CINV).

Methods

Sixty CINV patients were randomly divided into two groups. The control group received tropisetron hydrochloride, while the observation group received heat-sensitive moxibustion in addition to tropisetron hydrochloride. The treatment lasted for 7 days starting from the day of chemotherapy. The occurrence and severity of nausea and vomiting were recorded, and the complete remission rate was evaluated. The KPS score, quality of life scale score, and incidence of myelosuppression were compared between the two groups.

Results

The observation group showed lower incidence and severity of nausea and vomiting, higher complete remission rates, improved KPS score, and better quality of life compared to the control group. The incidence of myelosuppression was also lower in the observation group.

Conclusion

Heat-sensitive moxibustion combined with tropisetron hydrochloride effectively reduces nausea and vomiting after chemotherapy, improves quality of life, and relieves myelosuppression in patients with malignant tumors.

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