Study Overview
This study aimed to see if probiotics could help improve behavior and gut issues in children aged 2-9 with autism spectrum disorder (ASD).
Study Design
The research was a single-blinded, randomized, placebo-controlled trial conducted at five clinics.
Participants
180 children with ASD participated, divided into two groups: one received probiotics and the other received a placebo.
Intervention
Children took either a probiotic or placebo mixed in milk or water twice a day for three months.
Key Findings
- The probiotic group showed a significant decrease in behavioral issues, with a 47.77% improvement compared to 23.33% in the placebo group.
- Specific improvements included:
- Social withdrawal/lethargy: 40% reduction
- Stereotypic behavior: 37.77% reduction
- Hyperactivity: 34.44% reduction
- Inappropriate speech: 32.22% reduction
- Gut issues also improved, with significant reductions in constipation and diarrhea.
- Behavioral and gastrointestinal symptoms were found to be related.
Conclusions
Probiotic supplements can help improve both behavioral and gastrointestinal symptoms in children with ASD without any side effects. However, more research is needed with a larger group of children.
Next Steps for Clinics and Patients
- Define clear goals for using probiotics in treatment plans.
- Use AI tools to track and analyze the impact of probiotics on symptoms.
- Start with a pilot project to gather data and adjust treatment as needed.
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