Lithium versus anticonvulsants and the risk of physical disorders – Results from a comprehensive long-term nation-wide population-based study emulating a target trial

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Study on Bipolar Disorder Medication and Physical Disorders

Key Findings:

• Bipolar disorder is linked to higher rates of physical disorders.
• Study compared the effects of lithium, lamotrigine, and valproate on physical disorders.
• No significant differences found in the risk of physical disorders between the medications, except for myxedema.
• Lithium use was associated with a 7-10% higher risk of myxedema compared to lamotrigine or valproate.
• Overall, lithium did not increase the risk of developing most physical disorders.

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Full Clinical Trial Report Lithium versus anticonvulsants and the risk of physical disorders – Results from a comprehensive long-term nation-wide population-based study emulating a target trial: https://pubmed.ncbi.nlm.nih.gov/38663126/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1B1L42DK3a-JWCV4P_PtHHBmWjwBLFNcDXsYJkbqjQD0Ca7UQh&fc=None&ff=20240426043029&v=2.18.0.post9+e462414