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Molecular insights into clinical trials for immune checkpoint inhibitors in colorectal cancer: Unravelling challenges and future directions

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Colorectal Cancer and Immunotherapy

Colorectal cancer (CRC) is a complex disease with low survival rates, especially in advanced stages. Recent advancements in cancer treatment, particularly with immunotherapies targeting immune checkpoints, have shown promise in clinical trials.

Practical Solutions and Value

Immunotherapies like PD-1 inhibitors have been approved for treating certain types of advanced CRC.
However, these drugs only benefit a small percentage of patients, and resistance to immunotherapy is a significant issue.
Further research is needed to optimize the use of immunotherapy in CRC and identify biomarkers to predict treatment response.

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2024-04-25

Clinical trials

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