Rivaroxaban versus low molecular weight heparin for managing lower extremity deep vein thrombosis following thoracoscopic lung cancer surgery: a randomized controlled trial

Rivaroxaban vs. Low Molecular Weight Heparin for DVT Management

Study Overview

This study compares the effectiveness and safety of rivaroxaban and low molecular weight heparin (LMWH) for treating lower extremity deep vein thrombosis (DVT) after thoracoscopic lung cancer surgery.

Study Details

Sixty patients with DVT were randomly divided into two groups:

  • Experimental Group: 30 patients received rivaroxaban.
  • Control Group: 30 patients received LMWH.

Key patient information and ultrasound results were recorded before and after surgery. The patients were monitored for three months, with data collected at one and three months post-surgery.

Results

  • Both groups showed good wound healing after surgery.
  • D-dimer levels remained stable, indicating no new blood clots.
  • No serious complications like pleural effusion or gastrointestinal bleeding were reported.
  • Six patients in the control group had bruising at LMWH injection sites.

Conclusion

Rivaroxaban is as effective as LMWH for DVT treatment after lung cancer surgery and has a better safety profile.

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