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Saccharomyces boulardii combined with triple therapy alter the microbiota in the eradication of Helicobacter pylori infection

Study Title: Saccharomyces boulardii Combined with Triple Therapy for H. pylori Infection

Key Findings:

A clinical trial evaluated the effectiveness of combining Saccharomyces boulardii powder with triple therapy for eradicating H. pylori infection in patients with non-ulcer dyspepsia. The study included 144 patients and monitored microbial composition, eradication rates, symptom alleviation, and adverse reactions.

Results:

The combination of Saccharomyces boulardii with triple therapy showed promising results, with a higher eradication rate of 93.18% in the BRAC group compared to 75% in the SRAC group and 65.2% in the RAC group. Patients receiving Saccharomyces boulardii treatment also experienced a reduction in initial dyspepsia symptoms.

Practical Solutions and Value:

Combining Saccharomyces boulardii with triple therapy demonstrated notable efficacy in eradicating initial H. pylori infections among non-ulcer dyspepsia patients. This approach also showed advantages in alleviating symptoms, exhibited favorable tolerance, and maintained a high level of clinical safety.

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