Objective We studied how tumor cells behave in Chinese patients with mantle-cell lymphoma (MCL) and found they may grow faster than in Western patients. To address this, we designed a clinical trial to test a new treatment combining R-DA-EDOCH immunochemotherapy and R-DHAP therapy in young patients with newly diagnosed MCL. Methods We included 55 patients…
“`html Overview of the Study This study focuses on advanced gastric cancer (GC), a common and serious cancer with a poor outlook. Current treatments, like paclitaxel and nab-paclitaxel, are often not very effective. Researchers are exploring new combinations of treatments to improve patient outcomes. What is Being Tested? The study is testing a new combination…
Background Malnutrition is a common problem in intensive care units (ICUs), often caused by interruptions in enteral nutrition (EN). Aim of the Study This study looked at how often EN interruptions happen, why they occur, and how they affect patient nutrition in the ICU. Study Design This analysis involved 1,331 ICU patients who were receiving…
Background Anemia is a serious problem caused by malaria, and diagnosing it correctly is essential for proper treatment. Traditional laboratory tests to measure hemoglobin (Hb) levels, such as the Coulter Counter and Quantitative Buffy Coat® (QBC®), can be expensive and are not always available in low-resource areas. The HemoCue® test is a more affordable option…
Background Gastroenteritis is a leading cause of death in children worldwide, claiming around 3 million lives each year among those under 5 years old. Rotavirus is a significant cause of viral diarrhea in children aged 6 months to 2 years, leading to severe symptoms like watery diarrhea and vomiting. While supportive care and vaccines have…
Research Summary This study focused on treating anterior knee pain, a common issue caused by conditions like patellofemoral pain syndrome and patella tendon tendinitis. The goal was to compare the effectiveness of a digital therapeutic (DT) with standard care in helping patients. Study Design 140 participants with knee pain rated at 4 or higher on…
Study Overview This study focused on how a special nursing program that helps patients manage their water and salt intake can affect blood pressure and overall health in people with chronic kidney disease. Methodology From January 2020 to January 2023, 120 patients with chronic kidney disease were treated at our hospital. They were divided into…
Background Patients who have had stomach surgery often face issues like low blood sugar after meals and at night. Currently, they have to manage these problems on their own. This study looks at how nutrition can help improve these low blood sugar levels in patients with stomach cancer. Study Method This study involved patients aged…
“`html Introduction Many couples struggle with infertility, and despite improvements in assisted reproductive treatments, 70% of embryos still do not implant successfully. This can have serious personal and global effects. Research suggests that understanding a woman’s immune system in the uterus may help improve treatment outcomes. About the Study This study involved a trial with…
Background Managing locally advanced prostate cancer (PCa) and oligometastatic prostate cancer (OMPCa) is challenging. Because PCa can vary greatly from patient to patient, we need personalized treatment approaches. This study aims to see if using genomic markers to guide treatment can improve patient outcomes in a Chinese population. Methods This study is a phase II…
Mind-Body Therapy for Multiple Sclerosis Study Overview This study looked at whether Tension and Trauma Releasing Exercises (TRE) can help people with multiple sclerosis (PwMS) manage their symptoms, especially fatigue. Study Details The research was conducted over eight weeks with 28 participants from the Danish MS Society. They were divided into two groups: one group…
“`html Background Chronic heart failure is a serious condition with high rates of illness and death. About half of the patients diagnosed with it die within five years. New treatments like angiotensin receptor-neprilysin inhibitors (ARNIs) and sodium/glucose cotransporter 2 inhibitors (SGLT2is) have shown benefits in reducing death and hospital visits. However, it’s unclear if starting…
Introduction Melasma is a common skin condition that can be difficult to treat. A commonly used treatment is Hydroquinone at 4%, but it may have side effects. Study Objective This study aimed to compare the effectiveness of an anti-hyperpigmentation serum (Serum B3) containing niacinamide, tranexamic acid, vitamin C, and hydroxy acids against Hydroquinone. Study Design…
Study Overview This study looked at how well the Healthy Aging Brain Care Monitor (HABC-M) can track changes in older adults recovering from trauma. We compared it to established measures of mental health and well-being. Participants and Methods We analyzed data from 120 participants in a clinical trial focused on the Trauma Medical Home (TMH)…
Summary of Wound Healing Advancements This study highlights new techniques in healing wounds, focusing on a method called AIMED and a special cream called Lecoxen®. Study Overview Two medical centers in Italy tested the AIMED method on patients with different types of skin wounds. Patients were divided into two groups: one group used Lecoxen® cream,…
Background A dummy run was conducted to ensure the quality of intensity-modulated radiotherapy (IMRT) for elderly patients with newly diagnosed glioblastoma in a study by the Japan Clinical Oncology Group (JCOG1910). Methods 41 institutions participated in this study, each required to report their treatment plans for a benchmark case. They outlined the necessary volumes for…
Understanding the Study on Cognitive Training and Postoperative Delirium Objective This study aimed to find out if cognitive training (CT) can help reduce postoperative delirium (POD) in older patients who had total hip and knee surgeries. Methods The clinical trial took place from February 18 to July 10, 2023. It included patients aged 60 to…
MoKaRi Study Overview The MoKaRi study focuses on improving heart and metabolic health through diet. It examines how two different eating plans can reduce risks linked to heart disease. Study Details In this 20-week study, 65 participants with high levels of bad cholesterol (LDL-C) were involved. They were not taking any cholesterol-lowering medications. Each participant…
Summary of the HOMAGE Trial Findings The HOMAGE trial aimed to understand how diabetes (DM) and coronary artery disease (CAD) affect heart health and how the medication spironolactone can help. The study included 495 participants, mostly older adults, and looked at heart function and specific blood markers over 9 months. Key Findings Participants with diabetes,…
Background Pruritus, or itching, is a common skin issue that can be very uncomfortable. It can occur with various skin conditions and other health problems. Aim of the Study This study aimed to compare the effectiveness of three treatments for uremic pruritus: gabapentin, narrowband UVB therapy, and a combination of both. Methods The study involved…