Upper- vs Lower-Extremity Secondary Access During Transcatheter Aortic Valve Implantation: A Randomized Clinical Trial Importance The upper-extremity method for secondary access during Transcatheter Aortic Valve Implantation (TAVI) may lower the risk of bleeding at the access site. Objective This study aimed to compare the safety and effectiveness of upper-extremity access versus lower-extremity access in patients…
Impact of Medical Adhesives on Fluid Leakage at Injection Sites Objective The study aimed to see how effective medical glue is in stopping fluid leakage at needle insertion sites in patients with severe swelling. Methods Sixty patients with severe swelling were included in the study from June 2022 to June 2023. They were randomly divided…
Effects of 12-Week Supplementation with Coffee Diterpene Cafestol Study Overview This study looked at how cafestol, a compound found in coffee, affects healthy individuals with a larger waist size who are at risk of type 2 diabetes. Previous research shows coffee may help lower diabetes risk, but the effects of cafestol in humans needed more…
Individualised Computerised Cognitive Training (iCCT) for Mild Cognitive Impairment Overview This study explored the effects of Individualised Computerised Cognitive Training (iCCT) on cognitive abilities in people aged 60+ with Mild Cognitive Impairment (MCI). The iCCT uses machine learning to tailor exercises to each person’s skill level, making training more effective. Study Methods We compared iCCT…
Efficacy of Proinflammatory Cytokines in Pulpotomy Treatments Study Overview This study focused on how different pulpotomy agents affect inflammation levels and treatment success in children. Specifically, it compared levels of IL-6, IL-8, and a new biomarker, presepsin, to assess pulpal inflammation during treatment. Key Findings High Inflammation Levels: Elevated levels of IL-6, IL-8, and presepsin…
Intense Simplified Strategy for Type 2 Diabetes Management Study Overview This study aimed to see if a new treatment approach could help patients newly diagnosed with type 2 diabetes and high blood sugar levels. The approach includes a short period of intensive insulin therapy followed by oral medications. Study Details Design: A multicentre, open label,…
Evaluation of US Elastography in Thyroid Nodule Diagnosis: The ElaTION Randomized Control Trial Background There is mixed evidence regarding the benefits of using US elastography with fine-needle aspiration cytology (FNAC) compared to standard US-guided FNAC for thyroid nodules. Purpose This trial aimed to see if US elastography-guided FNAC could lower the rates of nondiagnostic results…
Impacts of Behavioral Activation on Psychological Distress in Cancer Patients Study Overview This study examined how behavioral activation (BA), a new type of psychological support, can reduce anxiety and psychological distress in patients with esophageal and gastric cancer in China. Methodology 139 patients participated, recruited between March and October 2023. They were randomly divided into…
Evaluating Platelet-Rich Plasma Injection in Spinal Surgery Study Overview This study looks at how effective and safe it is to use platelet-rich plasma (PRP) injections along with a specific spinal surgery known as percutaneous endoscopic nucleotomy for treating lumbar disc herniation (LDH) in younger adults. Study Details Between April 2022 and September 2023, 60 patients…
Study Overview: Targeted Axillary Dissection with Carbon Marking for Breast Cancer Background Neoadjuvant chemotherapy (NAC) can help breast cancer patients with lymph node metastases achieve complete responses, possibly eliminating the need for extensive lymph node removal. Traditional methods for targeted axillary dissection (TAD) using tissue markers have issues like marker loss and high costs. A…
Study Overview This study examines how ketamine and lamotrigine affect brain activity during negative emotional processing. It was conducted as a double-blind, randomized controlled trial using fMRI technology. Key Findings Ketamine’s Role: Ketamine is an effective antidepressant that influences brain circuits related to negative emotions. Lamotrigine’s Impact: Lamotrigine, which reduces glutamate release, can alter the…
Treatment of Post-Stroke Fatigue: A Simple Overview Objective The study aimed to see how a specific acupuncture technique affects fatigue in patients who have had a stroke. Methods Sixty-four patients with post-stroke fatigue were divided into two groups: Control Group: Received standard treatment plus Tongdu Tiaoshen acupuncture therapy. Observation Group: Received the same treatment as…
Acute Cardiovascular Responses of Postmenopausal Women to Resistance Training Sessions Study Overview This study will investigate how different types of resistance training affect cardiovascular health in postmenopausal women. Resistance training is often recommended to help with hormonal changes during menopause, but there are risks associated with intense exercises. This study aims to clarify these effects…
Comprehensive vs. Standard Remote Monitoring of Cardiac Devices in Heart Failure Patients Study Overview The ECOST-CRT study aimed to improve care for heart failure (HF) patients by comparing two types of remote monitoring (RM) for those with cardiac resynchronization therapy (CRT) devices. Study Design Patients were divided into two groups: Control Group: Standard daily RM,…
Effectiveness of NIPE Index for Pain Management in Young Children Background Assessing pain in infants is difficult because they cannot express themselves verbally. Current methods rely on observing behavior, which can lead to inconsistent pain assessments. The Newborn Infant Parasympathetic Evaluation (NIPE) index uses heart rate variability for a more objective pain assessment in children…
Clinical Trial Overview Title: Comparative clinical trial of Langenlianqiao oral liquid and Lianhuaqingwen capsule in treating mild COVID-19 cases. Published in: J Health Popul Nutr. 2024 Oct 12;43(1):158. Objective The goal of this study was to assess how effective Langenlianqiao (LGLQ) oral liquid is in treating COVID-19, providing valuable information for clinical treatment. Study Design…
Effects of Probiotic and Vitamin D Co-Supplementation on Migraine Study Overview This study explores how taking probiotics and vitamin D together can help adults with migraine headaches. It focuses on improving migraine symptoms, mental health, and inflammation levels. Background Migraine headaches are a significant health issue. Current migraine medications do not work for everyone and…
Effect of Heat Stress on Fetal and Infant Growth Source: Lancet Planet Health, October 2024 Background Climate change, food insecurity, and undernutrition are major issues affecting children’s health. This study looks at how heat impacts growth from conception to age 2, which is vital for understanding child mortality and health issues. Study Methods We analyzed…
Automated Detection of Neurodevelopmental Disorders Using Mobile Technology Overview Neurodevelopmental disorders (NDs) can have complex effects on children and may persist into adulthood. Identifying these disorders early is essential for effective intervention, yet many children go undiagnosed. Digital tools, especially serious games, offer innovative ways for clinicians to detect NDs. Study Goals This study investigates…
Study Overview This research compared the effects of Estetrol (E4) combined with Drospirenone (DRSP) versus Ethinyl estradiol (EE) combined with DRSP on blood coagulation and fibrinolysis in Japanese patients with endometriosis. Key Findings – E4/DRSP combination showed significantly less impact on coagulation and fibrinolysis compared to EE/DRSP. – Major anticoagulant proteins were less reduced in…