Accuracy of Healthcare Data in Identifying Cardiovascular Outcomes After Stroke Background Healthcare systems data (HCSD) can make clinical trials more efficient, but their accuracy is not always clear. This study aimed to evaluate how accurate HCSD is for detecting outcomes in the RESTART trial, comparing it to follow-up questionnaires. Methods RESTART was a clinical trial…
Effectiveness of Flaxseed and Fasting Mimicking Diet in Managing MASLD Study Overview This study explored how combining flaxseed and a fasting mimicking diet (FMD) affects patients with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). While both treatments have shown benefits individually, their combined effect was unclear. Study Design Conducted over 12 weeks, this randomized trial involved…
The Effect of High-Intensity Interval Training on Quality of Life and Chemotherapy Side Effects in Women With Breast Cancer Study Overview This study focuses on how high-intensity interval training (HIIT) affects the quality of life and side effects of chemotherapy in women with breast cancer (BC). Women undergoing neoadjuvant chemotherapy (NAC) often face various symptoms…
Selective Nociceptive Modulation with Transcutaneous KHFAC Stimulation Background Kilohertz high-frequency alternating current (KHFAC) stimulation is a method that can block nerves quickly without causing harm. Previous studies have tested frequencies from 5 to 20 kHz in humans, but few devices are approved for higher frequencies. This study aims to evaluate a new device that can…
Effects of Exercise and Diet on Abdominal Obesity Study Overview This study focused on how exercise and diet impact health markers in men with abdominal obesity. It involved 44 males, average age 34.7 years, who were divided into three groups: Exercise Group (EG): 16 participants did aerobic-resistance exercise for 6 weeks. Exercise + Diet Group…
Effectiveness of Treatment for Concussion-Related Convergence Insufficiency: The CONCUSS Study Study Overview The CONCUSS study is a clinical trial that aims to compare two treatment approaches for concussion-related convergence insufficiency (CONC-CI). It will evaluate: Immediate Office-Based Vergence/Accommodative Therapy with Movement (OBVAM) Delayed OBVAM (starting six weeks later) The study will also explore how the timing…
Effectiveness of the Smoke Free Smartphone App for Smoking Cessation Study Overview This study examined how effective the Smoke Free app is in helping people quit smoking compared to not receiving any support. Background Digital tools, like apps, can provide affordable ways to help people stop smoking. Study Objective We wanted to see if offering…
Utilization of Psychiatric Hospital Services Following Intensive Home Treatment A Nonrandomized Clinical Trial Importance: Home treatment (HT) has been linked to fewer days in the hospital but lacks proof of reducing overall psychiatric hospital service use (including inpatient treatment, home treatment, and day clinics). Objective: This study aimed to compare intensive home treatment (IHT) with…
Effects of Long-Term Almond Consumption on Health Study Overview This study looked at how eating almonds over a long time affects blood vessel health and heart-related risks in people with prediabetes. The research involved 34 participants who took part in a controlled trial with two phases: one where they ate almonds daily and another without…
The Impact of Curcumin on Inflammation in Lupus Patients Study Overview This study focused on how curcumin, a compound from turmeric, affects inflammation in patients with systemic lupus erythematosus (SLE), a chronic autoimmune disease. Study Design Seventy SLE patients aged 18-60 participated in this randomized, triple-blinded, placebo-controlled trial. Out of these, 62 completed the study.…
Impact of L-carnitine Supplementation on Children on a Ketogenic Diet Study Overview The ketogenic diet (KD) is high in fat, moderate in protein, and low in carbohydrates. This diet can affect how the stomach empties and how quickly food moves through the intestines. Purpose of the Trial The main goal of this clinical trial was…
Multicentre Randomised Controlled Trial on Shoulder Instability (STABLE): Study Overview Introduction Recurrent shoulder dislocations can damage the labrum and lead to bone loss in the shoulder. There are two main treatment options: soft tissue repair and bone augmentation. However, the best treatment for patients with some bone loss is still unclear, and current practices vary…
Cost-Effectiveness of Computer-Assisted Cognitive Behavioral Therapy for Depression Background About 1 in 5 adults experience depression, but less than half get help. Those with lower income and education face bigger challenges in accessing treatment. Computer-assisted cognitive behavioral therapy (CCBT) is a helpful and convenient method for treating depression, but we need to understand its cost-effectiveness…
Clinical Efficacy of Combined Treatments for Diabetic Foot Ulcers Objective This study investigates how autologous platelet-rich gel (APG) combined with continuous vacuum-sealed drainage (CVSD) and recombinant human acidic fibroblast growth factor (rh-aFGF) can help heal diabetic foot ulcers (DFU). The goal is to understand the healing process better and find new treatment options. Methods Ninety…
Conventional Colonoscopy vs. Cap-Assisted Colonoscopy Introduction Colonoscopy is the main method for diagnosing colorectal cancer. However, the results for detecting polyps and adenomas have varied with different devices. Objectives This study aims to see if there are differences in the diagnostic performance of conventional colonoscopy (CC) versus cap-assisted colonoscopy (CAC) for adenoma detection. Materials and…
Visual Performance of School-age Children Wearing Dual-Focus Soft Contact Lenses Background This study explores how dual-focus soft contact lenses (DFSCL) affect the vision of school-age children. Study Details We conducted a clinical trial with 64 children aged 8 to 12 years who needed vision correction. These children were divided into two groups: one group wore…
Study Overview: SIMUL-CHD Trial Purpose Effective communication between doctors and patients is essential, especially when discussing serious conditions like congenital heart diseases. To address communication challenges faced by medical professionals, we are introducing a simulation-based training program for pediatric cardiology trainees. This study will work with associations that support families of children with congenital heart…
Impact of Platelet-Rich Fibrin on Patient Recovery After Gum Surgery Study Overview This study looked at how platelet-rich fibrin (PRF) can help patients heal better after free gingival graft (FGG) surgery. PRF is a material that helps with tissue healing and can improve patient comfort and quality of life. What We Did We involved 39…
Respiratory Complications in Children Under Anesthesia Study Overview This study looked at how different anesthesia methods affect respiratory issues in young children during fiberoptic bronchoscopy (FOB). Objective The goal was to compare the effects of propofol, sevoflurane, and dexmedetomidine on respiratory complications in children aged 1 month to 3 years. Methods A total of 120…
Randomized Trial of Very Early Medication Abortion Background Medication abortion using mifepristone and misoprostol is proven to be safe and effective. However, there is limited data on its effectiveness when the pregnancy is very early and not visible through ultrasound. Methods We conducted a multicenter trial involving women seeking medication abortion within 42 days of…