Spirituality-Based Intervention in Hypertension: FEEL Trial Results Background Research shows that spirituality can improve health outcomes, but this area has not been extensively studied in clinical trials. Hypertension is a leading cause of heart-related health issues globally. Objectives This study aimed to see if a spirituality-based program could lower blood pressure (BP) and enhance blood…
Comparative Study on Hand Eczema Treatments Background Hand eczema is a common skin condition that affects many people and reduces their quality of life. Topical medications, like Clobetasol Propionate, are often used but may cause side effects with long-term use. This study will compare the effectiveness of two treatments: topical Tofacitinib 2% ointment and Clobetasol…
Evaluation of Loperamide’s Effect on Heart Rhythm Study Overview This study explored how loperamide, a medication, affects the heart’s repolarization interval. It looked at both loperamide and its metabolite (M1) to see if they prolong the QT interval at normal and high doses. Study Design The analysis used data from healthy adults in a controlled…
Impact of LT3 + LT4 Therapy on Quality of Life in Hypothyroid Patients Study Overview This study looked at how combining levothyroxine (LT4) and triiodothyronine (LT3) affects the quality of life in patients with primary hypothyroidism. Study Details A total of 151 Iranian patients diagnosed with primary hypothyroidism participated in this trial from 2020 to…
Role of Ivermectin and Colchicine in Treating COVID-19 Objective This study aimed to evaluate how effective ivermectin and colchicine are as treatments for COVID-19. Methodology A clinical trial was conducted with three groups at Ain Shams University Hospitals. Participants with moderate COVID-19 were included, while those under 18, over 65, or with other health issues…
Coronary CT Angiography for Stable Chest Pain: 10-Year Results from SCOT-HEART Trial Study Overview The SCOT-HEART trial showed that using coronary CT angiography (CCTA) improved the care of patients with stable chest pain. This study looks at whether these improvements last over time. Methods In this trial, patients aged 18-75 with possible stable angina were…
High Definition Transcranial Direct Current Stimulation for Alzheimer’s Dementia Overview This study explored a new, non-invasive technique to help with cognitive issues in Alzheimer’s dementia (AD). It aimed to see if this method could improve brain function in patients. Study Details The research was conducted at UT Southwestern Medical Center and involved 25 participants diagnosed…
Intranasal Oxytocin for Apathy in Frontotemporal Dementia (FOXY) Study Overview This study tested intranasal oxytocin as a treatment for apathy in people with frontotemporal dementia. Currently, there are no effective treatments for this condition. Key Findings Oxytocin was given every third day and showed a small improvement in apathy scores. Out of 94 participants, 40%…
Efficacy of Magnetic Therapy for Overactive Bladder Background Overactive bladder (OAB) affects about 12% of adults, especially as they age. Traditional treatments often have side effects and low patient adherence. This study compares two types of magnetic therapy for OAB patients. Study Details We conducted a randomized controlled trial with 45 OAB patients at The…
The Role of Butirprost® in Improving Antibiotic Treatment for Chronic Bacterial Prostatitis Overview Bacterial prostatitis (BP) is a common infection that causes pain and urinary issues in men, affecting their quality of life. Treatment usually involves antibiotics, but adding other supplements might improve results. This study focused on Butirprost® and its effects when used with…
Comparison of Kidney Damage in Different Colorectal Cancer Surgeries Study Overview Colorectal cancer is the third most common cancer affecting both men and women. With new technologies, less invasive surgical options are becoming more popular. This study compares kidney damage between laparoscopic (minimally invasive) and open surgeries for colon and rectal cancer using a specific…
Multistrategic Approaches in Treating Acute Migraine During Pregnancy Background and Objectives Migraine affects many women, especially during pregnancy when hormonal changes complicate treatment options. This study explores non-drug methods like physiotherapy, exercise, and relaxation techniques to help manage migraines in pregnant women. Study Overview Sixty pregnant women with acute migraines participated in this study. They…
Microneedle and Photodynamic Therapy for Oral Leukoplakia Objective To see if microneedle treatment can make photodynamic therapy (PDT) more effective and safer for oral leukoplakia. Methods A clinical trial was done with patients diagnosed with oral leukoplakia. They were split into two groups: Control Group: Received standard ALA-PDT. Experimental Group: Received microneedle treatment with lidocaine…
Prevalence of FGFR2b Protein Overexpression in Advanced Gastric Cancers Study Overview Purpose: FGFR2b protein overexpression is an important biomarker in gastric cancer. This study evaluated how common FGFR2b overexpression is in nearly 3,800 tumor samples from patients with advanced or metastatic gastric cancer (GC) during the prescreening for the Phase III FORTITUDE-101 trial. Methods: As…
Efficacy of Videoconferencing-Delivered Cognitive Behavioral Therapy for LGBTQ+ Anxiety Disorders Objective This study aims to evaluate the effectiveness of Cognitive Behavioral Therapy (CBT) delivered through videoconferencing for LGBTQ+ individuals experiencing anxiety disorders. While CBT is a proven treatment for anxiety in the general population, its effectiveness for LGBTQ+ individuals is still being explored. Methods We…
Study Overview Title: Hybrid Trial for Cervical Cancer Prevention in Uganda Published: PLoS One, January 24, 2025 Introduction Cervical cancer (CC) is a major health issue in Uganda, being the top cause of cancer deaths among women. Unfortunately, many women do not get screened for CC. A promising solution is to train women who have…
Symptomatic Improvement in Eosinophilic Esophagitis Key Findings from Recent Study Background: This study looked at why adults and teenagers with eosinophilic esophagitis (EoE) need more doses of dupilumab compared to other conditions. Study Methods: Researchers combined results from the phase 3 LIBERTY EoE TREET study, focusing on two main goals: Percentage of patients with 6…
Treatment of Peri-Implant Mucositis Study Overview This study compared the effectiveness of two treatments for peri-implant mucositis: an Er:YAG laser and an ultrasonic device. The goal was to see how these treatments affected pain, appearance, and overall quality of life over six months. Methods Each patient received one dental implant treatment. They were randomly assigned…
Study on the Effects of Autologous Serum and Artificial Tears Objective We wanted to see how autologous serum combined with artificial tears affects corneal sensation and tear film stability in patients with mild to moderate dry eyes after cataract surgery. Methodology We studied 150 patients with mild to moderate dry eyes after undergoing cataract surgery…
Lipidomic Profiling in Multiple Myeloma Patients Study Overview This study investigates how lipid profiling of blood samples can help identify biomarkers for predicting the effects of bortezomib (Btz) in patients with multiple myeloma (MM). Purpose The aim is to find specific metabolites that relate to toxicities and the effectiveness of Btz in newly diagnosed MM…