Conditions: Metastatic Castration-resistant Prostate Cancer
Sponsors: AstraZeneca; Merck Sharp & Dohme LLC
Recruiting
Real-World Clinical Experience of Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Olaparib + Abiraterone (PROceed)
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Clinical Research
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Clinical outcomes of selective removal to soft dentin versus firm dentin for deep caries lesions: a randomized controlled trial up to 5 years
Clinical Outcomes of Selective Dentin Removal for Deep Caries Study Overview This study compared two methods for treating deep caries in permanent teeth: selective removal to soft dentin (SRSD) with…
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Effect of Postbiotic Bifidobacterium longum CECT 7347 on Gastrointestinal Symptoms, Serum Biochemistry, and Intestinal Microbiota in Healthy Adults: A Randomised, Parallel, Double-Blind, Placebo-Controlled Pilot Study
Effect of Postbiotic Bifidobacterium longum CECT 7347 on Digestive Health Study Overview This study evaluated the impact of heat-treated Bifidobacterium longum CECT 7347 (HT-ES1) on digestive symptoms in healthy adults.…
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Real-world effectiveness and satisfaction with intravenous eptinezumab treatment in patients with chronic migraine: REVIEW, an observational, multi-site, US-based study
“`html Real-world Evidence Study Shows Positive Experiences with Eptinezumab for Chronic Migraine Background Despite advances in migraine treatment, many patients still face significant burden due to exclusion from traditional trials.…
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Effectiveness of Maintenance Electroconvulsive Therapy for Relapse Prevention in Clozapine-Resistant Schizophrenia
Understanding the MECT-RESIST Trial Results What the Trial Tested This study looked at whether maintenance electroconvulsive therapy (mECT) combined with standard treatment (called treatment as usual, or TAU) helps prevent…
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Implementation of Site-Specific Hepatitis C Virus Treatment Workflows for Vulnerable, High-Risk Populations: A Prospective Single-Arm Trial
Hepatitis C Treatment for Vulnerable Populations Introduction Hepatitis C virus (HCV) can be effectively treated with new medications, but many vulnerable groups struggle to access this treatment. Objective This study…
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Correlation Between MG Symptoms PRO and Existing MG-Specific Outcome Scores in the Phase 3 MycarinG Study: Post Hoc Analysis (P1-11.026)
Understanding the Myasthenia Gravis Study Results Objective This study aimed to understand how well the Myasthenia Gravis (MG) Symptoms Patient-Reported Outcome (PRO) scale relates to other measures of daily living…
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Efficacy of Zhuangdan Yanshi Decoction with Dapoxetine in Treating Premature Ejaculation: A Clinical Study
Understanding the Study Results This study looked at how well a combination of Zhuangdan Yanshi Decoction and dapoxetine hydrochloride works for treating premature ejaculation, especially in patients with specific symptoms…
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Prevalence of FGFR2b Protein Overexpression in Advanced Gastric Cancers During Prescreening for the Phase III FORTITUDE-101 Trial
Prevalence of FGFR2b Protein Overexpression in Advanced Gastric Cancers Study Overview Purpose: FGFR2b protein overexpression is an important biomarker in gastric cancer. This study evaluated how common FGFR2b overexpression is…
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Adherence to a low-fat dietary pattern reduces head and neck cancer risk: evidence from the PLCO trial
Adherence to a Low-Fat Diet Lowers Head and Neck Cancer Risk Study Overview The study focused on how a low-fat dietary pattern (LFD) affects the risk of head and neck…
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Study of comparison of medical thoracoscopic guided biopsy versus closed pleural biopsy for etiological diagnosis of undiagnosed exudative pleural effusions: A randomized controlled study
Study Overview This study compares two methods for diagnosing unknown causes of fluid in the lungs: medical thoracoscopy (MT) and closed pleural biopsy (CPB). Background Medical thoracoscopy is popular for…
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“Using Machine Learning to Predict Periodontal Therapy Response in Diabetic Patients”
Understanding the Study Results This study looked at how different factors affect the success of gum disease treatment in patients with diabetes. The researchers used advanced computer techniques to analyze…
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Lipidomic profiling of plasma from patients with multiple myeloma receiving bortezomib: an exploratory biomarker study of JCOG1105 (JCOG1105A1)
Lipidomic Profiling in Multiple Myeloma Patients Study Overview This study investigates how lipid profiling of blood samples can help identify biomarkers for predicting the effects of bortezomib (Btz) in patients…
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Oral fluid supplementation for the prevention of post-dural puncture headache: A noninferiority randomized controlled trial
Study Overview This study aimed to understand how different advice on drinking fluids affects the occurrence of headaches after a lumbar puncture, a common medical procedure. Study Design We conducted…
