Conditions: Metastatic Castration-resistant Prostate Cancer
Sponsors: AstraZeneca; Merck Sharp & Dohme LLC
Recruiting
Real-World Clinical Experience of Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Olaparib + Abiraterone (PROceed)
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Clinical Research
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Comparison of endoscopic versus focused parathyroidectomy in surgical management of single-gland primary hyperparathyroidism: a randomized clinical trial
Comparison of Endoscopic versus Focused Parathyroidectomy in Surgical Management of Single-Gland Primary Hyperparathyroidism: A Randomized Clinical Trial Key Findings: The success rate for endoscopic parathyroidectomy was 95.3% compared to 77.1%…
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Equitable Care for Hypertension: Blood Pressure and Patient-Reported Outcomes of the RICH LIFE Cluster Randomized Trial
Equitable Care for Hypertension: Blood Pressure and Patient-Reported Outcomes of the RICH LIFE Cluster Randomized Trial Key Findings RICH LIFE study compared two interventions for hypertension control: standard of care…
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Economic evaluation of an adjunctive intraocular and peri-ocular steroid vitreoretinal surgery for open globe trauma: Cost-effectiveness of the ASCOT randomised controlled trial
Economic Evaluation of ASCOT Trial for Eye Trauma Background In the UK, around 5,000 people suffer eye injuries each year, with 250 resulting in permanent blindness. This study looks at…
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The Effects of Art Therapy and Psychosocial Skills Training on Symptoms and Social Functioning in Patients with Schizophrenia and Their Relatives
The Effects of Art Therapy and Psychosocial Skills Training on Symptoms and Social Functioning in Patients with Schizophrenia and Their Relatives Objective The study aimed to evaluate and compare the…
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Assessing the effectiveness of the SOLIO Alfa Cure Plus device in treating low back pain: a randomized controlled study
Assessing the Effectiveness of the SOLIO Alfa Cure Plus Device for Low Back Pain Study Overview Nonspecific low back pain (LBP) is a major global health issue, affecting 84% of…
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Brief use of behavioral activation features predicts benefits of self-help app on depression symptoms: Secondary analysis of a selective prevention trial in young people
Objective This study aimed to find out how using a cognitive behavioral therapy (CBT) self-help app can help reduce depression in young people at risk. Method In a recent trial,…
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Effect of Prostate Cancer Education on Saudi Men: Knowledge, Beliefs, and Screening Intentions
Effect of Prostate Cancer Education on Saudi Men: Knowledge, Beliefs, and Screening Intentions Asian Pac J Cancer Prev. 2024 Jul 1;25(7):2439-2444. doi: 10.31557/APJCP.2024.25.7.2439. Abstract Purpose: This study aimed to assess…
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Clinical study on the treatment of Qingfei Paidu Granules combined with nondrug therapy for asymptomatic patients with novel coronavirus
Summary of Clinical Study on Qingfei Paidu Granules and Nonpharmacological Interventions for Asymptomatic COVID-19 Patients Background The study evaluated the effectiveness of Qingfei Paidu Granules (QFPG) and nonpharmacological interventions in…
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Evaluation of the Effect of Loperamide on the Cardiac Repolarization Interval Using Exposure-Response Analysis
Evaluation of Loperamide’s Effect on Heart Rhythm Study Overview This study explored how loperamide, a medication, affects the heart’s repolarization interval. It looked at both loperamide and its metabolite (M1)…
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Fast Track Pathway to Accelerated Cholecystectomy Versus Standard of Care for Acute Cholecystitis (FAST) pilot trial
Background When patients have acute cholecystitis, the timing of surgery can vary. Some patients have surgery early (within 7 days), while others may have it later (after 7 days). Early…
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Unused potential of lipid-lowering therapy in very high-risk patients with atherosclerotic cardiovascular disease. A retrospective data analysis
“`html Research Summary In a study published in Nutr Metab Cardiovasc Dis, researchers investigated the use of lipid-lowering therapy (LLT) and lifestyle changes in patients with atherosclerotic cardiovascular disease (ASCVD)…
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Feasibility and acceptability of the Comprehensive Oncology Rehabilitation and Exercise (CORE) clinical workflow algorithm in patients with newly diagnosed stage I-III breast cancer who undergo surgery as first-line treatment
Cancer Clinical Trial Summary Background This study explored a new approach called the Comprehensive Oncology Rehabilitation and Exercise (CORE) algorithm. It aims to connect women diagnosed with breast cancer to…
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Reducing Inappropriate Antibiotic Use for URTIs: Effective Strategies for Healthcare Professionals
Understanding the Trial Results This study looked at how to reduce unnecessary antibiotic use for common illnesses like colds and flu, which are known as upper respiratory tract infections (URTIs).…
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Predicting Sciatic Nerve Block Success: The Role of Perfusion Index and Blood Flow Changes
Understanding the Study on Sciatic Nerve Blocks What Was the Study About? This study looked at how well sciatic nerve blocks work. It focused on two main things: the Perfusion…
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Cefazolin versus placebo for surgical antibiotic prophylaxis in low-risk cesarean delivery: a feasibility blinded randomized controlled trial
Background Antibiotics before cesarean delivery are generally recommended for all patients, but there are concerns about their effects on infants. This study tested the processes of a clinical trial involving…
