Conditions: Metastatic Castration-resistant Prostate Cancer
Sponsors: AstraZeneca; Merck Sharp & Dohme LLC
Recruiting
Real-World Clinical Experience of Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Olaparib + Abiraterone (PROceed)
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Clinical Research
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Diagnosing Solid Lesions in the Pancreas With Multimodal Artificial Intelligence: A Randomized Crossover Trial
Diagnosing Solid Lesions in the Pancreas With Multimodal Artificial Intelligence: A Randomized Crossover Trial Summary Artificial intelligence (AI) can help diagnose solid lesions in the pancreas from endoscopic ultrasonographic (EUS)…
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Effectiveness of extracorporeal shock wave therapy on functional ability in grade IV knee osteoarthritis — a randomized controlled trial
Effectiveness of Extracorporeal Shock Wave Therapy on Functional Ability in Grade IV Knee Osteoarthritis Summary Extracorporeal shockwave therapy (ESWT) is a non-invasive treatment for knee osteoarthritis (OA). This study aimed…
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Enhancing Serious Illness Conversations in the Emergency Department for Older Adults
Understanding the Trial Results What Worked? The study showed that a special program called the ED GOAL intervention helped doctors document conversations about patients’ end-of-life wishes more effectively. This means…
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Parsimonious versus extensive bleeding score: can we simplify risk stratification after percutaneous coronary intervention and reduce bleeding events by de-escalation of the antiplatelet strategy?
Understanding Bleeding Risk After Heart Procedures Study Overview This study compares two methods for assessing bleeding risk after a heart procedure called percutaneous coronary intervention (PCI). The goal is to…
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Evaluating a digital tool for supporting people affected by breast cancer: a prospective randomized controlled trial-the ADAPT study
Evaluating a Digital Tool for Breast Cancer Support: The ADAPT Study Purpose: This study examines how a digital tool aids self-management for individuals affected by breast cancer. It focuses on…
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Cost-Effectiveness of Team-Based Coaching With Surveillance for Prevention of Acute Kidney Injuries
Importance of Preventing Kidney Injuries Over 10% of patients in the US who undergo certain procedures face serious kidney injuries, leading to higher healthcare costs and health issues. Effective prevention…
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Effect of utilizing either a self-reported questionnaire or administrative data alone or in combination on the findings of a randomized controlled trial of the long-term effects of antenatal corticosteroids
Effect of Utilizing Different Data Sources on Clinical Trial Findings Key Findings: A study investigated the impact of using self-reported questionnaires, administrative data, or a combination of both on the…
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Assessing the efficacy and safety profiles of 0.025% tretinoin in treating axillary hyperpigmentation with acanthosis nigricans: a randomized double-blinded study
Study Overview This study looked at how effective and safe a 0.025% tretinoin cream is for treating dark skin patches (hyperpigmentation) in the armpits caused by a skin condition called…
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Efficacy and underlying mechanisms of three-circle post standing qigong on insomnia in college students: a four-arm, double-blind, randomized controlled trial protocol
Efficacy and Mechanisms of TCPS Qigong for Insomnia in College Students Protocol for a Double-Blind, Randomized Controlled Trial Background: Insomnia in college students is often overlooked despite its impact on…
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Lay-Led Intervention for War and Refugee Trauma: A Randomized Clinical Trial
Lay-Led Intervention for War and Refugee Trauma: A Randomized Clinical Trial Importance The global refugee crisis disproportionately affects the Muslim world, leading to trauma-related mental health issues. Effective psychotherapy exists,…
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A Digital Cognitive-Physical Intervention for Attention-Deficit/Hyperactivity Disorder: Randomized Controlled Trial
Study Title: A Digital Cognitive-Physical Intervention for Attention-Deficit/Hyperactivity Disorder: Randomized Controlled Trial Background ADHD is a common neurodevelopmental disorder in children. This study aimed to assess the effectiveness of BrainFit,…
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Long-Term Effects of Repeat Antenatal Corticosteroids on Adult Offspring Health: Insights for Clinicians
Understanding the Trial Results The study looked at the long-term effects of repeat doses of antenatal corticosteroids given to pregnant women at risk of preterm birth. The main findings are:…
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Epigallocatechin gallate enhances sympathetic heart rate variability and decreases blood pressure in obese subjects: a randomized control trial
Study Title: Epigallocatechin gallate enhances sympathetic heart rate variability and decreases blood pressure in obese subjects: a randomized control trial Summary This study investigated the effects of epigallocatechin gallate (EGCG)…
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Findings From the Todurujo na Kadurok (Empowering Youth) HIV Self-Testing and Edutainment Comic Randomized Controlled Trial With Refugee Youth in a Humanitarian Setting in Uganda
Findings From the Todurujo na Kadurok (Empowering Youth) HIV Self-Testing and Edutainment Comic Trial Introduction Humanitarian areas often lack access to HIV self-testing (HIV-ST). Methods We conducted a trial to…
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Different daily times for at-home bleaching with 10% carbamide peroxide: A randomized single-blind, noninferiority controlled trial
Study on At-Home Teeth Bleaching with 10% Carbamide Peroxide Background This study tested if using 10% carbamide peroxide (CP) for 2 or 4 hours daily is as effective as using…
