Conditions: Leukemia, Myeloid, Acute
Interventions: Drug: DFP-10917; Drug: Venetoclax
Sponsors: Delta-Fly Pharma, Inc.
Not yet recruiting
Phase I/II Study of DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia
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Clinical Research
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A randomized controlled educational pilot trial of interictal epileptiform discharge identification for neurology residents
“`html Summary of Clinical Trial Results A study was conducted to evaluate the effectiveness of an educational program using technology-enhanced learning to teach neurology residents how to identify interictal epileptiform…
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Characterizing HIV drug resistance in cases of vertical transmission in the VESTED randomized antiretroviral treatment trial
Characterizing HIV Drug Resistance in Vertical Transmission Cases Study Overview The VESTED trial compared the safety and effectiveness of three different antiretroviral treatment regimens in pregnant and postpartum women with…
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Reliability of impedance spectroscopy versus digital radiograph and ICDAS-II in occlusal caries detection: a prospective clinical trial
Reliability of Impedance Spectroscopy in Occlusal Caries Detection Key Findings: The study compared the performance of alternating current impedance spectroscopy (ACIST) with digital radiograph (DR) and ICDAS-II in detecting occlusal…
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Impact of probiotic supplements on behavioural and gastrointestinal symptoms in children with autism spectrum disorder: A randomised controlled trial
Study Overview This study aimed to see if probiotics could help improve behavior and gut issues in children aged 2-9 with autism spectrum disorder (ASD). Study Design The research was…
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Detection of hypovolemia by non-invasive hemodynamic monitoring during major surgery using Ringers solution, 5% albumin, or 20% albumin as infusion fluid: a post-hoc analysis of a randomized clinical trial
Background Fluid loading is a common treatment for major bleeding, but it can sometimes lead to too much fluid in the body. We looked at different ways to replace fluids…
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Evaluating the efficacy of N-acetylcysteine in diminishing the duration and frequency of rotavirus-induced gastroenteritis: a preliminary randomized, placebo-controlled, double-blind clinical trial
Background Gastroenteritis is a leading cause of death in children worldwide, claiming around 3 million lives each year among those under 5 years old. Rotavirus is a significant cause of…
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Curcumin-Piperine Combination Shows Promise in Reducing Inflammation in Sepsis Patients
Understanding the Trial Results This study looked at how a combination of curcumin and piperine could help patients with sepsis, a serious condition caused by infections. The trial involved 66…
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Effectiveness of extracorporeal shock wave therapy on functional ability in grade IV knee osteoarthritis — a randomized controlled trial
Effectiveness of Extracorporeal Shock Wave Therapy on Functional Ability in Grade IV Knee Osteoarthritis Summary Extracorporeal shockwave therapy (ESWT) is a non-invasive treatment for knee osteoarthritis (OA). This study aimed…
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Early CPAP Therapy for Spinal Cord Injury: Improving Sleep Efficiency and Motor Recovery
Understanding the OPTIMISE SCI Trial Results The OPTIMISE SCI trial looks at how treating sleep problems can improve recovery for people with spinal cord injuries (SCI). This study is important…
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Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT
Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT Practical Solutions and Value Highlights Atopic eczema is a common childhood skin problem connected with asthma and…
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A randomised clinical trial comparing a surgical approach for treatment of peri-implantitis to non-surgical debridement with adjunctive diode laser therapy
A Randomised Clinical Trial on Peri-Implantitis Treatment Objective The study aimed to compare the effectiveness of non-surgical treatment with diode laser therapy to surgical methods for managing peri-implantitis. Materials and…
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Evaluation of an Updated Gene Panel as a Diagnostic Tool for Both Male and Female Infertility
“`html Summary of Study on Infertility Genes In recent years, there has been a growing identification of genes linked to male and female infertility. This has expanded the scope of…
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Pentoxifylline ameliorates subclinical atherosclerosis progression in patients with type 2 diabetes and chronic kidney disease: a randomized pilot trial
Pentoxifylline Reduces Subclinical Atherosclerosis in Patients with Type 2 Diabetes and Chronic Kidney Disease Key Findings: Pentoxifylline (PTF) shows positive effects on the progression of subclinical atherosclerosis (SA) in patients…
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Enhancing foster care relationships through attachment-based intervention: the safe families study protocol, a randomized controlled trial of the circle of security parenting program()
Enhancing Foster Care Relationships through Attachment-Based Intervention Study Overview The Circle of Security Parenting program® (COS-P) aims to strengthen the relationships between foster carers and children. This program is especially…
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Feasibility of robotic-assisted surgery in advanced rectal cancer: a multicentre prospective phase II study (VITRUVIANO trial)
Feasibility of Robotic-Assisted Surgery in Advanced Rectal Cancer: VITRUVIANO Trial Key Findings The study assessed the outcomes of robotic surgery in patients with locally advanced rectal cancer. The results highlighted…
