Conditions: Leukemia, Myeloid, Acute
Interventions: Drug: DFP-10917; Drug: Venetoclax
Sponsors: Delta-Fly Pharma, Inc.
Not yet recruiting
Phase I/II Study of DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia
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Morning stiffness analyzer: AI checks for autoimmune arthritis signs
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Clinical Research
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Enhancing Liver Function and Alleviating Depression in Triple Negative Breast Cancer with Shugan Jieyu San: A Clinical Study
Understanding the Study This study looked at a Traditional Chinese Medicine called Shugan Jieyu San. It aimed to see if this medicine could help improve liver function and reduce depression…
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EEG-Guided Learning Boosts Cognitive Control and Academic Success in ADHD Children
Understanding EEG-Guided Adaptive Learning for Children with ADHD What is ADHD? Attention Deficit Hyperactivity Disorder (ADHD) affects a child’s ability to focus, control impulses, and perform well in school. Traditional…
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Early detection and a treatment bundle strategy for postpartum haemorrhage: a mixed-methods process evaluation
Early Detection and Treatment for Postpartum Haemorrhage Overview Postpartum haemorrhage is a major cause of maternal death. A study called E-MOTIVE showed that a specific intervention could reduce serious outcomes…
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Effect of oral nintedanib vs placebo on epistaxis in hereditary hemorrhagic telangiectasia: the EPICURE multicenter randomized double-blind trial
Effect of Oral Nintedanib vs Placebo on Epistaxis in Hereditary Hemorrhagic Telangiectasia Study Overview Epistaxis, or nosebleeds, significantly impacts patients with hereditary hemorrhagic telangiectasia (HHT). Nintedanib, known for its ability…
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Clinical application of third-generation dual-source CT-based dynamic imaging reconstruction for pulmonary embolism imaging
Clinical Application of Advanced CT Imaging for Pulmonary Embolism Background This study evaluates the effectiveness of a new CT imaging method for diagnosing pulmonary embolism (PE). It focuses on improving…
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“Combining Sensorimotor and Core Strength Training to Alleviate Low Back Pain in Adult Scoliosis: A Clinical Trial Overview”
Understanding the Trial Results This study looked at how well sensorimotor training (SoMT) combined with core strength training (CST) can help adults with low back pain and scoliosis. Here’s what…
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“Improving Pediatric Cardiac Arrest Outcomes: Comparing Airway Management Techniques”
Understanding the Trial Results The study looked at two ways to help children who have a cardiac arrest outside of a hospital. One method used a device called i-gel® for…
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Phase II Study of Defactinib (VS6063) in Patients With Tumors With NF2 Loss: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol U
Phase II Study of Defactinib (VS6063) in Patients With Tumors With NF2 Loss Overview of the Study The NCI-MATCH trial focused on patients with various cancers, assigning them targeted therapies…
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Effect of endothelin-1 on the blood pressure response to acute hypoxia and hyperoxia in healthy young men
Effect of Endothelin-1 on Blood Pressure Response to Hypoxia and Hyperoxia in Young Men Physiological Reports, 2024 Sep;12(17):e70004 Endothelin-1 (ET-1) and its receptors have been linked to increased sensitivity to…
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Ruxolitinib Cream Outperforms Triamcinolone for Mild to Moderate Atopic Dermatitis
Understanding the Trial Results This study compared two types of creams for treating atopic dermatitis (AD), a common skin condition. The creams are: Ruxolitinib Cream (1.5%): A nonsteroidal cream. Triamcinolone…
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Teach back educational strategy on knowledge about breast cancer among low health literate women
Teach-Back Educational Strategy for Breast Cancer Knowledge Background This study explores how a “teach-back” educational method helps women with low health literacy understand breast cancer better. Methods The research was…
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Metastatic sites of baseline as predictors in recurrent or metastatic nasopharyngeal carinoma treated with PD-L1 inhibitor: a secondary analysis of multicenter, single-arm, phase II study (KL-A167)
Study Overview This study examines how the location of metastatic sites affects the treatment outcomes of recurrent or metastatic nasopharyngeal carcinoma (R/M NPC) patients receiving a PD-L1 inhibitor called KL-A167.…
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Comparing visual inspection with acetic acid, with and without Lugol’s Iodine for triage of HPV self-sample positive women in Ethiopia: a randomized controlled trial
Background Many women with high-risk HPV (hrHPV) can heal from infections without treatment. The World Health Organization suggests using Visual Inspection with Acetic Acid (VIA) as a follow-up test during…
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MRI Tumor Regression Response to Neoadjuvant Chemotherapy Alone without Radiation for Rectal Adenocarcinoma
MRI Tumor Regression Response to Neoadjuvant Chemotherapy Alone without Radiation for Rectal Adenocarcinoma Summary This study investigated the accuracy of MRI in assessing pathologic complete response in patients with locally…
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Predictors of VNS Therapy Response in Treatment-Resistant Depression: Insights for Clinicians
Understanding the RECOVER Trial Results What is Vagus Nerve Stimulation (VNS)? VNS is a treatment for people with severe depression that hasn’t improved with other therapies. It involves a device…
