Conditions: Solid Tumor, Adult; BRCA1 Mutation; BRCA2 Mutation; Ovarian Cancer; Breast Cancer; Prostate Cancer
Interventions: Drug: ACE-86225106 tablet
Sponsors: Acerand Therapeutics (Shanghai) Limited
Recruiting
Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors
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Clinical Research
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Improving Caregiver Support: Effective Strategies for Enhancing Mood and Health in Cancer Patients Undergoing Chemotherapy
Main Findings of the Study This study looked at how a supportive care program helps cancer patients and their caregivers during chemotherapy. The results showed that the program improved the…
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Nalbuphine vs. Sufentanil: Optimizing Propofol Use in Hysteroscopy Anesthesia
Main Findings of the Study Researchers compared two pain relief medications, nalbuphine and sufentanil, during a specific type of surgery called hysteroscopy. They wanted to see which drug needed less…
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Erector Spinae Plane Block Reduces Analgesic Use in Laparoscopic Nephrectomy: A Study on Postoperative Pain Management
Understanding the Trial Results This study looked at a method called the erector spinae plane block (ESPB) used for pain relief in donors undergoing laparoscopic kidney removal. Here’s what we…
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Nanocarbon vs. Methylene Blue: Enhancing Sentinel Lymph Node Biopsy Accuracy in Breast Cancer
Understanding the Study Results This study looked at two types of dyes used in a procedure called sentinel lymph node biopsy, which is important for breast cancer patients. The two…
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Study on the Mechanism of Nd:YAG Laser-Assisted Therapy on the Changes of Subgingival Flora in Periodontitis
Study on Nd:YAG Laser Therapy for Periodontitis Purpose This study looked at how effective Nd:YAG laser therapy is when combined with traditional cleaning methods for patients with severe periodontitis. We…
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Multicenter Prospective Randomized Comparison of Ultrasound-Guided Stellate Ganglion Versus Thoracic Paravertebral Block for Sympathetic Blockade in Chronic Upper Extremity Pain
Understanding Clinical Trials on Pain Relief Techniques What Was Studied? This study looked at two methods to relieve pain in the arms and hands: Stellate Ganglion Block (SGB) and Thoracic…
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Internet and Telephone Support for Discontinuing Long-Term Antidepressants: The REDUCE Cluster Randomized Trial
Internet and Telephone Support for Discontinuing Long-Term Antidepressants: The REDUCE Cluster Randomized Trial ABSTRACT There is concern about long-term antidepressant treatment, and this trial aimed to assess the safety and…
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A three-gene expression score for predicting clinical benefit to anti-PD-1 blockade in advanced renal cell carcinoma
“`html Study Summary In a recent study, researchers aimed to develop a gene expression score to predict the clinical benefit of the anti-PD-1 antibody nivolumab in patients with advanced clear…
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Cognitive Screening for MCI: MoCA’s Reliability in Patients with Depression
Understanding the Study Results The study looked at how depression affects cognitive testing in older adults. It specifically used a test called the Montreal Cognitive Assessment (MoCA) to see if…
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Effective Communication Strategies to Reduce Antibiotic Expectations in Patients
Understanding the Trial Results This research looked at how doctors can communicate better when discussing illnesses and antibiotic treatments. It aimed to help patients have clearer expectations about antibiotics, which…
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Low-calorie diets and remission of type 2 diabetes in Chinese: phenotypic changes and individual variability
Study Overview This study explored how low-calorie diets can help Chinese individuals with type 2 diabetes (T2D) achieve remission. Unlike other ethnic groups, Chinese people have unique characteristics related to…
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A 2.6% Benzoyl Peroxide AV Cleanser Specifically Designed for Sensitive Skin Offers Good Efficacy and Tolerability
Study Highlights: 2.6% Benzoyl Peroxide AV Cleanser for Sensitive Skin Effective and Well-Tolerated Treatment for Acne Vulgaris A clinical study evaluated the efficacy and safety of a 2.6% Benzoyl Peroxide…
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A clinical trial on pelvic floor sensory testing in women with and without stress urinary incontinence
Clinical Trial on Pelvic Floor Sensory Testing This study focuses on understanding how pelvic floor sensory training can help women with stress urinary incontinence (SUI). It compares the sensory abilities…
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Pilot feasibility study to determine the utility of direct access and quantitative magnetic resonance cholangiopancreatography (MRCP) in the assessment of suspected acute biliary or ductal gallstone presentations
Pilot Study on Direct MRCP for Gallstone Assessment Background Patients suspected of having gallstones usually get an abdominal ultrasound. However, if liver function tests (LFTs) are abnormal, they often undergo…
