Conditions: Primary Aldosteronism; Finerenone; Mineralocorticoid Receptor Antagonist
Interventions: Drug: Finerenone
Sponsors: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Recruiting
The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism
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Clinical Research
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Multi-study feasibility analysis on a composite biomarker of inflammatory resilience to quantify the effects of energy restriction on low-grade inflammation in overweight and obese individuals
Purpose Understanding how nutrition affects health in people with metabolic issues is difficult. We need sensitive tools to measure this. A new method called phenotypic flexibility helps us see how…
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Anaerobutyricum soehngenii improves glycemic control and other markers of cardio-metabolic health in adults at risk of type 2 diabetes
Study Overview Anaerobutyricum soehngenii, a safe and beneficial gut microbe, has shown promise in improving insulin sensitivity in people at risk for type 2 diabetes. A recent study tested its…
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Evaluation of a FlpA Glycoconjugate Vaccine with Ten N-Heptasaccharide Glycan Moieties to reduce Campylobacter jejuni Colonisation in Chickens
“`html Evaluation of a FlpA Glycoconjugate Vaccine to Reduce Campylobacter jejuni Colonisation in Chickens Published in Vaccines (Basel) on April 9, 2024 Campylobacter is a common cause of stomach illness…
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High-intensity interval training improves insulin sensitivity in individuals with prediabetes
Objective This study aimed to explore how low-volume high-intensity interval training (HIIT) and walking, compared to no exercise, affect insulin sensitivity and metabolism in individuals with prediabetes. Study Design Participants…
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Sibling-Support for Adolescent Girls (SSAGE): A study protocol for a pilot randomized-controlled trial of a whole-family, gender transformative approach to preventing mental illness among forcibly displaced adolescent girls
Study Title: Sibling-Support for Adolescent Girls (SSAGE) Objective: Preventing Mental Illness among Forcibly Displaced Adolescent Girls Forcibly displaced adolescent girls are at higher risk for mental illness, especially due to…
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Can resistance prehabilitation training bring additional benefits in valvular cardiac surgery? protocol for a randomized controlled trial
Resistance Prehabilitation in Valvular Cardiac Surgery: A Clinical Trial Protocol Introduction Cardiovascular diseases (CVD) often require major surgery for treatment. Fast-track rehabilitation programs have shown promise in reducing postoperative complications…
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Clinical breakage, slippage and acceptability of two commercial ultra-thin polyurethane male condoms compared to a commercial thin latex condom: a randomised, masked, 3 way crossover, multi centre controlled study (SAGCS 2)
Study Title: Clinical Trial on Ultra-Thin Polyurethane Condoms Published in Reprod Health, 2024 Sep 4;21(1):128 Objective: Evaluate breakage, slippage, and acceptability of two ultra-thin polyurethane condoms against a thin latex…
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Efficacy of a Mobile Health-Based Behavioral Treatment for Lifestyle Modification in Type 2 Diabetes Self-Management: Greenhabit Randomized Controlled Trial
Efficacy of a Mobile Health-Based Behavioral Treatment for Lifestyle Modification in Type 2 Diabetes Self-Management: Greenhabit Randomized Controlled Trial Background Using digital tools can help patients with type 2 diabetes…
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Efficacy of Intravenous Canrenone for Sinus Rhythm Restoration in Atrial Fibrillation Patients
Understanding the Trial Results of Canrenone for Atrial Fibrillation This study looked at whether intravenous canrenone could help patients with atrial fibrillation (AF) get their heart rhythm back to normal.…
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Assessment of a randomized controlled trial on the safety of pre-placing bronchial balloons in transbronchial lung cryobiopsy for diagnosing interstitial lung disease
Assessment of Safety in Diagnosing Interstitial Lung Disease Rationale and Objectives Bleeding is a common complication of transbronchial lung cryobiopsy (TBLC). This study aimed to determine if pre-placing a bronchial…
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Dark Chocolate Mitigates Premenstrual Performance Impairments and Muscle Soreness in Female CrossFit() Athletes: Evidence from a Menstrual-Phase-Specific Trial
Nutrients and Female Athletic Performance Hormonal changes during the menstrual cycle can affect female athletes’ physical performance, muscle function, and mental processing, especially before their period. This study looked at…
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“Improving Outcomes for Opioid Use Disorder: Impact of Hospital Addiction Consult Services”
Understanding the Trial Results This clinical trial looked at how a special hospital service for addiction can help patients with opioid use disorder after they leave the hospital. Here’s what…
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Impact of Vojta therapy combined with standard care on psychometric and functional parameters in patients with chronic lower back pain: a randomized controlled trial
Impact of Vojta Therapy on Chronic Lower Back Pain Key Findings: Combining Vojta therapy (VT) with standard care and electrotherapy significantly improved posture, reduced depression, and enhanced self-esteem in patients…
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Privacy-Preserving Training-as-a-Service (PTaaS): A Novel Service Computing Paradigm that Provides Privacy-Friendly and Customized Machine Learning Model Training for End Devices
Here’s the simplified and clear language version of the provided text: “**On-device Intelligence (ODI) and Privacy-Preserving Training-as-a-Service (PTaaS): Practical Solutions for AI Model Training** On-device intelligence (ODI) combines mobile computing…
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An Overview of Advancements in Deep Reinforcement Learning (Deep RL)
Advancements in Deep Reinforcement Learning (Deep RL) Deep reinforcement learning (Deep RL) combines reinforcement learning (RL) and deep learning to achieve remarkable success in complex tasks, including superhuman game performance.…
