Conditions: Primary Aldosteronism; Finerenone; Mineralocorticoid Receptor Antagonist
Interventions: Drug: Finerenone
Sponsors: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Recruiting
The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism
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Clinical Research
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Effectiveness of King’s Theory of Goal Attainment in Blood Glucose Management for Newly Diagnosed Patients With Type 2 Diabetes: Randomized Controlled Trial
Effectiveness of King’s Theory of Goal Attainment in Blood Glucose Management Overview Diabetes is a major health issue worldwide, with millions affected. In China, around 140 million people have diabetes,…
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Intraoral appliance treatment modulates inflammatory markers and oxidative damage in elderly with sleep apnea
Intraoral Appliance Treatment for Sleep Apnea in Elderly Patients Study Overview This study focuses on how an intraoral appliance (IOA) can help elderly patients with obstructive sleep apnea (OSA). OSA…
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Assessing the impact of a self-guided digital intervention for fear of cancer recurrence (iConquerFear) in ovarian cancer survivors: a pilot randomised waitlist-controlled trial
Background About half of ovarian cancer survivors experience a strong fear of their cancer coming back, which makes it hard for them to cope with life after treatment. This study…
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Use of pronase in screening for early cancers of the upper gastrointestinal tract
Study Overview: This research focused on how effective pronase is in finding early cancer and improving visibility during gastroscopy in China. Study Details: 1450 patients were part of a program…
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Estimating minimal important change of the National Institutes of health research task force impact score using computer adaptive measures: a secondary analysis of two randomized clinical trials in a military population with chronic pain
Study Overview This study focuses on the National Institutes of Health (NIH) Research Task Force impact score, which measures pain intensity, pain interference, and physical function in patients with chronic…
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A preliminary study of further attempt at the development, testing and application of an auxiliary equipment for electronic colonoscopy
A Preliminary Study on Improving Electronic Colonoscopy Background Colonoscopy is an important tool for screening colorectal cancer and routine health checks, becoming more common each year. In China, nurses typically…
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Efficacy of dry needling with the fascial winding technique in reducing the percentage of surgery in carpal tunnel syndrome: A randomized clinical trial
“`html Carpal Tunnel Syndrome Treatment: Key Results from a Clinical Trial Background Many methods exist to treat carpal tunnel syndrome (CTS). This study explores how effective dry needling (DN) is…
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Bone Pain and Survival Among Patients With Metastatic, Hormone-Sensitive Prostate Cancer: A Secondary Analysis of the SWOG-1216 Trial
Bone Pain and Survival Among Patients With Metastatic, Hormone-Sensitive Prostate Cancer: A Secondary Analysis of the SWOG-1216 Trial Summary: The study aimed to compare survival outcomes among patients with metastatic,…
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Results from a first-in-human phase i safety trial to evaluate the use of a vascularized pericranial/temporoparietal fascial flap to line the resection cavity following resection of newly diagnosed glioblastoma
“`html Summary of Clinical Trial Findings Purpose Glioblastoma (GBM) treatment limitations due to systemic toxicity and blood-brain barrier (BBB) permeability Use of vascularized flaps to bypass BBB and improve access…
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Comprehensive multi-omics analysis of resectable locally advanced gastric cancer: Assessing response to neoadjuvant camrelizumab and chemotherapy in a single-center, open-label, single-arm phase II trial
“`html Study Title: Comprehensive Analysis of Neoadjuvant Camrelizumab and Chemotherapy for Locally Advanced Gastric Cancer Background The study aimed to evaluate the effectiveness of combining neoadjuvant camrelizumab with chemotherapy in…
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Shortness of breath on exertion? Check for early signs of heart failure
How the Chatbot Works If you’ve ever felt winded after climbing stairs or doing light chores, you’re not alone. This chatbot helps you understand whether shortness of breath during activity…
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Evaluating the Efficacy of a Digital Therapeutic (CT-152) as an Adjunct to Antidepressant Treatment in Adults With Major Depressive Disorder: Protocol for the MIRAI Remote Study
Evaluating the Efficacy of a Digital Therapeutic (CT-152) as an Adjunct to Antidepressant Treatment in Adults With Major Depressive Disorder: Protocol for the MIRAI Remote Study ABSTRACT Major depressive disorder…
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Efficacy of mobile phone intervention to increase male partner antenatal care attendance for HIV testing in Moshi municipal, Tanzania: a randomized controlled trial
“`html Study Summary: Increasing Male Partner Involvement in Antenatal Care Background HIV partner counselling and testing in antenatal care (ANC) is important, but male involvement in ANC is low in…
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Adjunctive ketamine vs. buprenorphine in co-occurring major depressive disorder and opioid use disorder: a randomized, double-blind clinical trial assessing anxiety symptom severity and craving intensity
Clinical Trial Overview This clinical trial, conducted on April 17, 2025, focused on patients who have both Major Depressive Disorder (MDD) and Opioid Use Disorder (OUD). These conditions create significant…
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Administration of Calcium and Magnesium in Acute Intracerebral Hemorrhage Patients: Assessing Safety and Feasibility
Background Calcium and magnesium levels in the blood are important for blood clotting and may affect how brain bleeding (intracerebral hemorrhage or ICH) worsens. This study aimed to maintain specific…
