Conditions: Type 1 Diabetes Mellitus; Type 1 Diabetes Mellitus With Hypoglycemia; Drive
Interventions: Device: MiniMed 780 G
Sponsors: University Hospital, Motol
Not yet recruiting
Glycemic Excursions in Patients With Type 1 Diabetes Mellitus Using Closed-loop Systems
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Clinical Research
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ATGL links insulin dysregulation to insulin resistance in adolescents with obesity and hepatosteatosis
Understanding Insulin Resistance in Adolescents This study looks at how insulin resistance (IR) affects teenagers with obesity, especially focusing on fat tissue in their bodies. Key Findings Researchers tested 30…
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Feasibility, Effectiveness, and Acceptability of a Telemedicine Neurological Consultation for Drug-Induced Movement Disorders; A Randomized Pilot Study
“`html Telemedicine for Drug-Induced Movement Disorders Background People taking certain medications may develop movement disorders. It’s crucial to identify and manage these issues early to prevent them from worsening. Neurologists…
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Cefazolin versus placebo for surgical antibiotic prophylaxis in low-risk cesarean delivery: a feasibility blinded randomized controlled trial
Background Antibiotics before cesarean delivery are generally recommended for all patients, but there are concerns about their effects on infants. This study tested the processes of a clinical trial involving…
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Population pharmacokinetic modeling of asciminib in support of exposure-response and ethnic sensitivity analyses in patients with chronic myeloid leukemia
Background The study focused on a drug called asciminib for patients with chronic myeloid leukemia (CML) in the chronic phase. The goal was to improve how we understand the drug’s…
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Efficacy of a Novel Moisturizing Cream in Reducing Neurovascular Hyper-Reactivity in Sensitive Skin
What Was the Trial About? This trial looked at a new moisturizing cream to help people with sensitive skin. Sensitive skin can feel uncomfortable or painful when it comes into…
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Reliability and usability of a portable spirometer compared to a laboratory spirometer
Background Access to spirometry, a test for lung function, is often limited because traditional spirometers are expensive and not easy to use. This can make it hard to diagnose and…
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Effects on Child Development and Parent-Child Interaction of the FACAM Intervention: A Randomized Controlled Study of an Interdisciplinary Intervention to Support Women in Vulnerable Positions through Pregnancy and Early Motherhood
Effects of FACAM Intervention on Child Development and Parent-Child Interaction Study Overview Published in the International Journal of Environmental Research and Public Health, this study evaluated the impact of the…
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Low-calorie diets and remission of type 2 diabetes in Chinese: phenotypic changes and individual variability
Study Overview This study explored how low-calorie diets can help Chinese individuals with type 2 diabetes (T2D) achieve remission. Unlike other ethnic groups, Chinese people have unique characteristics related to…
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Effect of early administration of tetracosactide on mortality and host response in critically ill patients requiring rescue surgery: a sensitivity analysis of the STOPSHOCK phase 3 randomized controlled trial
Effect of Early Administration of Tetracosactide on Mortality and Host Response in Critically Ill Patients Requiring Rescue Surgery Summary Early administration of tetracosactide (TCS10) in critically ill patients undergoing rescue…
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Rucaparib Shows Promise in HRDsig+ Solid Tumors: Key Insights for Oncology Professionals
Trial Results Explained The LODESTAR study looked at a drug called rucaparib for treating solid tumors in patients with specific genetic changes. Here’s what we found: What Worked? Rucaparib showed…
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Could TREM-1 be a novel marker in the diagnosis of fibromyalgia?: A cross-sectional study
Study Summary: Could TREM-1 be a Novel Marker in the Diagnosis of Fibromyalgia? Key Findings: Researchers investigated the potential role of TREM-1 in the context of fibromyalgia syndrome (FMS) and…
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Enhancing CP/CPPS Treatment: The Role of Psychological Interventions in Patient Recovery
Understanding the Study Results This study looked at how adding therapy for mental health, called psychological intervention (PI), can help patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). This condition…
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A Case of Multiple Brain Tuberculomas in the Subarachnoid Cisterns: Recognition of Radiological Characteristics Regarding the Development of Paradoxical Response during Antituberculosis Treatment
“`html Practical Solutions and Value in Clinical Trial Case Study: Multiple Brain Tuberculomas in the Subarachnoid Cisterns Recognition of Radiological Characteristics Development of Paradoxical Response during Antituberculosis Treatment Brain tuberculoma…
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Possibilities of Azilsartan Medoxomil for Preparation for Planned Percutaneous Coronary Intervention in Patients With Type 2 Diabetes Mellitus
Possibilities of Azilsartan Medoxomil for Preparation for Planned Percutaneous Coronary Intervention in Patients With Type 2 Diabetes Mellitus Key Findings Evaluation of the efficacy and safety of azilsartan medoxomil for…
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18F-Prostate-Specific Membrane Antigen PET/CT imaging for potentially resectable pancreatic cancer (PANSCAN-2): a phase I/II study
18F-Prostate-Specific Membrane Antigen PET/CT Imaging for Pancreatic Cancer (PANSCAN-2) Study Overview This study explored the use of 18F-PSMA PET/CT imaging to detect potentially resectable pancreatic cancer, specifically pancreatic ductal adenocarcinoma…
