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Comparison of novel PSMA-targeting [177Lu]Lu-P17-087 with its albumin binding derivative [177Lu]Lu-P17-088 in metastatic castration-resistant prostate cancer patients: a first-in-human study
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Clinical Research
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Study protocol of the PRINCESS trial-PReoperative INtermittent fasting versus CarbohydratE loading to reduce inSulin resiStance versus standard of care in orthopaedic patients: a randomised controlled trial
Study Overview of the PRINCESS Trial The PRINCESS trial investigates how different preoperative nutritional strategies affect insulin resistance in orthopedic patients undergoing surgery. Background Surgery can cause metabolic stress, leading…
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Cost-effectiveness of C-reactive protein point of care testing for safely reducing antibiotic consumption for acute exacerbations of chronic obstructive pulmonary disease as part of the multicentre, parallel-arm, open, individually randomised, controlled PACE trial
Cost-Effectiveness of C-Reactive Protein Testing for Antibiotic Use in COPD Study Overview This study evaluated the use of C-reactive protein point-of-care testing (CRP-POCT) to help reduce unnecessary antibiotic prescriptions in…
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Cost-effectiveness and cost-benefit analyses of fluoride varnish for caries prevention in Guangxi, China
Cost-effectiveness and Cost-benefit of Fluoride Varnish for Caries Prevention Summary This study evaluated the cost-effectiveness and cost-benefit of fluoride varnish (FV) interventions for preventing caries in the first permanent molars…
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The comparative study of letibotulinum toxin A and onabotulinum toxin A in treatment of primary axillary hyperhidrosis
Understanding Primary Axillary Hyperhidrosis Primary axillary hyperhidrosis (PAH) is a condition where individuals experience excessive sweating in their underarms. This can be challenging and affect daily life. Treatment Options The…
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Safety and efficacy of genomic biomarker-guided neoadjuvant therapy for locally advanced and oligometastatic prostate cancer (SEGNO): study protocol for an open-label prospective phase II umbrella clinical trial
Background Managing locally advanced prostate cancer (PCa) and oligometastatic prostate cancer (OMPCa) is challenging. Because PCa can vary greatly from patient to patient, we need personalized treatment approaches. This study…
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Association of energy source with outcomes in en bloc TURB: secondary analysis of a randomized trial
Study Overview This study evaluates the effectiveness of different energy sources used in a procedure called en-bloc transurethral resection of bladder tumors (ERBT). The goal is to understand how these…
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Advancing Healthcare Equity in Nephrology: Addressing Racial and Ethnic Disparities in Research Trials and Treatment Strategies
“`html Addressing Gender and Racial Inequalities in Nephrology Key Points: Women from underrepresented racial groups face challenges in kidney disease research due to lack of representation. Systemic biases in healthcare…
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Editor-in-chief page
Leveraging AI for Smarter Healthcare: Meet the Visionary Behind aidevmd.com At aidevmd.com, we bridge the gap between artificial intelligence and clinical excellence. Since our accreditation in 2016, our mission has…
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Effectiveness of a multimodal therapy protocol for the management of allergic rhinitis: a randomized controlled trial
Effectiveness of a Multimodal Therapy for Allergic Rhinitis Study Overview This study investigates how well a multimodal therapy works for treating allergic rhinitis. Study Design We conducted a randomized controlled…
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Effectiveness of interventions to improve adherence to antidepressant medication in patients with depressive disorders: a cluster randomized controlled trial
“`html The Importance of Adherence to Antidepressant Medication for Patients with Depressive Disorders Depression is a common mental health disorder affecting millions worldwide. Antidepressant medication is a commonly prescribed treatment,…
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Repetitive transcranial magnetic stimulation for stimulant use disorders (STIMULUS): protocol for a multi-site, double-blind, randomized controlled trial
Background Cocaine and methamphetamine use disorders are serious health issues. Unfortunately, there are currently no FDA-approved treatments available for these conditions. The STIMULUS study is a clinical trial that aims…
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Can the combination of citicoline and vitamin B12 be beneficial in the healing of corneal nerves after corneal cross-linking?
Can Citicoline and Vitamin B12 Help Heal Corneal Nerves After Cross-Linking? Study Overview This study looked at how topical citicoline, vitamin B12, and hyaluronic acid (OMK2 eye drops) affect the…
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Healing potentiality of blood clot, S-PRF and A-PRF as scaffold in treatment of non-vital mature single rooted teeth with chronic peri-apical periodontitis following regenerative endodontic therapy: randomized clinical trial
Healing Potential of Blood Clot, S-PRF, and A-PRF in Treating Non-Vital Teeth Overview This study explored how effective different regenerative treatments are for treating necrotic mature teeth with chronic periapical…
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Phase II Study of Samotolisib in Children and Young Adults With Tumors Harboring Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Pathway Alterations: Pediatric MATCH APEC1621D
Phase II Study of Samotolisib in Children and Young Adults With Tumors Harboring PI3K/mTOR Pathway Alterations Practical Solutions and Value Highlights: Clinical trials play a vital role in developing safe…
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Potential Harms of Feedback After Web-Based Depression Screening: Secondary Analysis of Negative Effects in the Randomized Controlled DISCOVER Trial
Background Web-based depression screenings are commonly used, often providing automated feedback to users. However, there are concerns about potential negative effects, and clear evidence is lacking. Objective The goal of…
