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The Prognostic Value of the Systemic Immune-Inflammation Index (SII) and Red Cell Distribution Width (RDW) in Patients with Cervical Cancer Treated Using Radiotherapy

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The Prognostic Value of Blood Test Indices in Cervical Cancer Patients

Introduction:

There is increasing interest in using routine blood tests like RDW and SII to predict survival in cancer patients receiving radiotherapy. This study aimed to assess the connection between pre-treatment RDW and SII levels and overall survival (OS) in patients with localized cervical cancer undergoing radiotherapy.

Material and Methods:

  • Retrospective analysis of 249 patients with stage IB2-IVA cervical cancer treated with definitive radiotherapy between 2011 and 2017.
  • Statistical analysis used Kaplan-Meier method, log-rank tests, and Cox proportional hazards models.

Results:

  • Patients with low RDW and low SII had significantly longer OS.
  • Low RDW was an independent prognostic factor for survival.
  • Including RDW in the model improved the prediction accuracy.

Conclusions:

RDW is a cost-effective and widely available prognostic factor for survival in cervical cancer patients undergoing radiotherapy. It could enhance pre-treatment prognosis assessments and aid in identifying candidates for treatment escalation.

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Full research The Prognostic Value of the Systemic Immune-Inflammation Index (SII) and Red Cell Distribution Width (RDW) in Patients with Cervical Cancer Treated Using Radiotherapy: https://pubmed.ncbi.nlm.nih.gov/38672624/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1B1L42DK3a-JWCV4P_PtHHBmWjwBLFNcDXsYJkbqjQD0Ca7UQh&fc=None&ff=20240427133354&v=2.18.0.post9+e462414

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