Fluorescence-Guided Laparoscopy after Oral Hypericin Administration for Staging of Locally Advanced Gastric Cancer-A Pilot Study

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Fluorescence-Guided Laparoscopy for Staging of Gastric Cancer

Practical Solutions and Value

• Hypericin, a fluorescent compound from plants, was tested to improve visualization of peritoneal metastasis (PM) in gastric cancer (GC) through laparoscopy.
• Study aimed to assess safety and feasibility of oral hypericin and the effectiveness of fluorescence-guided laparoscopy (FGL) for staging GC.
• Patients received Laif® 900, a hypericin-containing product, before undergoing white and ultraviolet light laparoscopy.
• Findings showed that FGL was feasible but did not significantly improve PM detection in this study.
• Authors suggested ensuring sufficient hypericin levels in target tissue before reconsidering FGL with hypericin.

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Full research Fluorescence-Guided Laparoscopy after Oral Hypericin Administration for Staging of Locally Advanced Gastric Cancer-A Pilot Study: https://pubmed.ncbi.nlm.nih.gov/38673695/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1B1L42DK3a-JWCV4P_PtHHBmWjwBLFNcDXsYJkbqjQD0Ca7UQh&fc=None&ff=20240427133354&v=2.18.0.post9+e462414