The Influence of Diet Therapy and Physical Training on MCP-1 Secretion in Obese Patients with Coronary Heart Disease
Key Findings:
After a 12-week intervention, participants experienced significant improvements including:
- 4.0% reduction in body weight
- 4.2% decrease in waist circumference
- 5.4% reduction in visceral fat
- 9.8% decrease in total cholesterol
- 16.6% decrease in LDL-cholesterol
- 26% decrease in triglycerides
- 10.33% improvement in the results of the 6-minute walk test
- 2.8 times reduction in LPS-stimulated monocytes secretion of MCP-1 (p=0.005)
Conclusion:
The study suggests that a specialized diet and regular physical activity may decrease the proinflammatory activity of monocytes in obese patients with coronary heart disease.
Practical Solutions:
Implementing a specialized diet with reduced simple carbohydrates and salt, along with daily intake of cruciferous vegetables, seasonal dark berries, and green tea, in conjunction with regular assisted physical trainings, could be beneficial for obese patients with coronary heart disease.
