Determining the optimal frequency of SARS-CoV-2 regular asymptomatic testing: A randomized feasibility trial in a home care setting

Determining the optimal frequency of SARS-CoV-2 regular asymptomatic testing: A randomized feasibility trial in a home care setting

Background

The SARS-CoV-2 pandemic has posed challenges for caregivers in home care settings, as they can transmit the virus to their high-risk relatives. Regular asymptomatic testing of caregivers may help reduce transmission, but the best testing frequency is unknown.

Methods

We conducted a trial enrolling caregivers providing home-based care for a relative at least twice a week. Participants were randomly assigned to conduct saliva-based antigen self-testing once a week, twice a week, or every two days. They completed weekly questionnaires, and data on mask use was collected.

Results

All participants completed the study, and high rates of self-test adherence were observed in all groups. No SARS-CoV-2 infections were detected. However, mask adherence decreased during the study.

Conclusion

The study demonstrated that regular self-testing was feasible and well-tolerated by participants. However, it may have led to decreased protective behavior. A future definitive trial should be performed during high SARS-CoV-2 prevalence as a multicentre study to confirm the impact of regular asymptomatic testing on infection transmission.

Trial Registration

The trial is registered with the German Clinical Trials Register, DRKS00026234.

Clinical Trials and AI-Driven Solutions

Clinical trials are essential for developing safe and effective treatments. Our AI-driven platform, DocSym, consolidates ICD-11 standards, clinical protocols, and research into a single, easily accessible knowledge base for clinicians.

In today’s healthcare environment, streamlining operations is crucial. Our mobile apps support scheduling, monitoring treatments, and telemedicine, making it easier to manage patient care and expand services digitally.

By using AI, clinics can enhance their workflows and improve patient outcomes, reducing paper routines. Learn more about how we can help at aidevmd.com.