Integration of the PD-L1 inhibitor atezolizumab and WT1/DC vaccination into standard-of-care first-line treatment for patients with epithelioid malignant pleural mesothelioma-Protocol of the Immuno-MESODEC study

Integration of Immuno-MESODEC Study into Epithelioid Malignant Pleural Mesothelioma Treatment

Key Points

Malignant pleural mesothelioma (MPM) is a very aggressive cancer with a poor prognosis.

The Immuno-MESODEC study aims to integrate PD-L1 inhibitor atezolizumab and WT1/DC vaccination into the first-line treatment for epithelioid MPM patients.

It is a multicenter, single-arm, phase I/II trial designed to evaluate safety, feasibility, clinical efficacy, and immunogenicity of this treatment approach.

If successful, this novel combination strategy could become a promising advanced treatment option for this challenging cancer.

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