Combination of a monofocal and one type of extended depth-of-focus (zonal refractive) intraocular lens (COMEDI) in bilateral cataract surgery protocol: a monocentric, randomised, parallel group trial in cataract surgery

COMEDI Study: Improving Cataract Surgery Outcomes

Introduction

The COMEDI study explores the benefits of combining monofocal and extended depth-of-focus (EDOF) intraocular lenses (IOLs) in cataract surgery. EDOF lenses offer a wider range of vision compared to monofocal lenses, and are a promising alternative to multifocal lenses which can cause visual side effects.

Methods and Analysis

This study involves 88 bilateral cataract patients and compares the outcomes of combined monofocal and EDOF IOL implantation versus bilateral monofocal IOL implantation. The primary measure is distance corrected intermediate visual acuity, with additional assessments including near visual acuity, reading speed, patient-reported spectacle independence, contrast sensitivity, and more at the 3-month follow-up.

Ethics and Dissemination

The study protocol has been approved by the ethical committee of the University Hospital of Brussels. The trial is registered under NCT06002399.

Clinical Trial Benefits

Clinical trials like COMEDI are essential for improving treatments. Our AI-driven platform, DocSym, consolidates clinical knowledge and protocols to support clinicians. Additionally, our mobile apps streamline patient care and support telemedicine, helping clinics to enhance their workflows and improve patient outcomes.

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