Community-engaged randomised controlled trial to disseminate COVID-19 vaccine-related information and increase uptake among Black individuals in two US cities with rheumatic conditions

Community-Engaged Trial to Increase COVID-19 Vaccine Uptake in Black Individuals with Rheumatic Conditions

Published in BMJ Open, August 24, 2024

Background: In the US, there are disparities in COVID-19 infection and vaccine uptake among historically marginalized racial and ethnic groups. People with rheumatic conditions, especially those who are immunocompromised, are at higher risk for severe infection, with significant racial inequities in outcomes and vaccine uptake. Structural racism and misinformation contribute to these inequities.

Method: A community-based trial comparing the effectiveness of training trusted community leaders with rheumatic conditions using a racial justice vs a biomedical framework to increase COVID-19 vaccine uptake and reduce hesitancy. The trial began in February 2024 in Boston and Chicago. Eligible community leaders will receive specific training and then disseminate the information to their social network members.

Outcome: The primary outcome will be the COVID-19 vaccine uptake among the social network members of the trained community leaders, compared between the two intervention groups.

Results: The trial has received ethical approval and will be published in a peer-reviewed journal.

Trial Registration Number: NCT05822219

PMID: 39181556 | DOI: 10.1136/bmjopen-2024-087918

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