Percentage Area Reduction as a Prognostic Indicator in Diabetic Foot Ulcer Treatment
J Wound Care. 2024 Sep 1;33(Sup9):S36-S42
Early indicators of healing are crucial for effective treatment of diabetic foot ulcers (DFUs). A post hoc analysis of a large multicentre prospective randomized controlled trial revealed that a percentage area reduction (PAR) of >50% at week 4 is a strong prognostic indicator for complete healing by week 12 in patients treated with standard of care (SoC).
Practical Solutions and Value
These findings provide valuable information for timely intervention in hard-to-heal DFUs, reducing the risk of complications such as soft tissue infection and lower extremity amputation. The use of PAR at week 4 as a prognostic indicator allows for rapid evaluation of treatment efficacy and safety, supporting streamlined patient care and improved outcomes.
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