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Efficacy and safety of choline alphoscerate for amnestic mild cognitive impairment: a randomized double-blind placebo-controlled trial

Efficacy and Safety of Choline Alphoscerate for Amnestic Mild Cognitive Impairment

Study Overview

This study investigated the effectiveness and safety of choline alphoscerate (αGPC) in individuals with mild cognitive impairment. Participants were randomly assigned to receive either αGPC or a placebo for 12 weeks.

Key Findings

After 12 weeks, those who received αGPC showed a significant improvement in cognitive function compared to the placebo group. The αGPC group had a decrease of 2.34 points on the Alzheimer’s Disease Assessment Scale-cognitive subscale (ADAS-cog).

Safety and Conclusion

No serious adverse events were reported, and participants did not discontinue the intervention due to side effects. The study suggests that αGPC is a safe and effective intervention for individuals with mild cognitive impairment.

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