Effective Treatment for Knee Osteoarthritis with PRP Injections
Study Overview: This study investigates the effectiveness of autologous platelet rich plasma (PRP) injections in treating knee osteoarthritis (KOA). It examines how these injections affect important biomarkers: interleukin-1 beta (IL-1β), tumor necrosis factor-alpha (TNF-α), and high-sensitivity C-reactive protein (hs-CRP).
Methodology:
150 KOA patients from the Third Hospital of Bethune were randomly divided into two groups:
- Control Group: Treated with etocoxib.
- Observation Group: Treated with PRP injections along with etocoxib.
The study compared the effectiveness, biomarkers, and knee function scores after treatment.
Results:
- The observation group showed a 94.67% effectiveness rate compared to 84.00% in the control group.
- Significant improvements in biomarkers and knee function scores were observed at 1 and 2 months post-treatment.
- PRP injections led to lower levels of IL-1β, TNF-α, and hs-CRP, and higher knee function scores.
Conclusion:
PRP injections significantly enhance knee function and reduce inflammation in KOA patients, proving to be a highly effective treatment option.
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