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Evaluation and randomised controlled trial of home urinalysis testing in patients with SLE at elevated risk for developing lupus nephritis: a study protocol

Evaluation of Home Urinalysis Testing in Patients with SLE

Study Overview

This study focuses on lupus nephritis (LN), a common issue for patients with systemic lupus erythematosus (SLE). Up to 60% of adult SLE patients may develop LN, which can lead to serious kidney problems. Minority groups often face worse outcomes, making early detection crucial.

Practical Solutions

We are testing a home urine sampling method combined with text message reminders to help patients at high risk for LN. The study will have two phases:

  • Phase 1: A pilot trial with 18 participants to assess feasibility and gather feedback.
  • Phase 2: A larger trial with 160 participants to compare the effectiveness of home testing against standard care.

Value of the Study

The goal is to see if weekly home urine tests can detect kidney issues earlier than traditional methods. Early detection could lead to better treatment and improved health outcomes.

Future Implications

The results will help shape future home testing methods and improve patient care through timely interventions.

Registration

This trial will be registered on ClinicalTrials.gov before participant enrollment begins.

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