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Safety and effectiveness of dual therapy for Helicobacter pylori infection and the effect on the glycated hemoglobin level in type 2 diabetes

Safety and Effectiveness of Dual Therapy for H. pylori Infection in Diabetes

Study Overview

This study focuses on patients with type 2 diabetes who are at a higher risk of failing H. pylori treatment. We evaluated the safety and effectiveness of a dual therapy using vonoprazan and amoxicillin (VA) for treating H. pylori infection in these patients.

Key Findings

  • The study involved 75 patients with type 2 diabetes and H. pylori infection.
  • Patients received VA dual therapy for 14 days.
  • The success rate of H. pylori eradication was 84% overall and 87% in those who followed the treatment plan closely.
  • Factors that increased the risk of treatment failure included smoking and high glycated hemoglobin (A1C) levels.
  • Patients who successfully eradicated H. pylori showed a significant decrease in A1C levels three months after treatment.

Practical Solutions and Value

VA dual therapy is a safe and effective option for treating H. pylori in patients with type 2 diabetes. By addressing H. pylori infection, we can help improve blood sugar control in these patients.

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