Appendicectomy vs. Antibiotics for Appendicitis in Children
Study Overview
This study compares two treatments for uncomplicated appendicitis in children: surgery (appendicectomy) and antibiotics. It aims to see if antibiotics are as effective as surgery.
Study Details
Conducted across 11 children’s hospitals in multiple countries, this trial included children aged 5-16 with suspected appendicitis. Participants were randomly assigned to either the antibiotic group or the appendicectomy group.
Key Findings
- Out of 936 enrolled patients, 846 completed the study with follow-up data.
- Treatment failure occurred in 34% of the antibiotic group, compared to only 7% in the surgery group.
- No deaths or serious adverse events were reported in either group.
- Antibiotic treatment was found to be less effective than surgery.
Conclusions
Antibiotics for treating non-perforated appendicitis are less effective than appendicectomy based on the study’s findings.
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