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Mitomycin C augmented canalicular silicone intubation versus external dacryocystorhinostomy in primary acquired nasolacrimal duct obstruction: a retrospective study

Study Overview

This study compares two treatments for a condition called primary acquired nasolacrimal duct obstruction (NLDO), which affects tear drainage from the eye. The two treatments are:

  • External Dacryocystorhinostomy (DCR)
  • Canalicular Silicone Intubation with Mitomycin C (MMC)

Study Details

In this research, 60 patients diagnosed with NLDO were studied at Menoufia University Hospital in Egypt from June 2021 to July 2023. Patients were divided into two groups:

  • 30 patients underwent external DCR
  • 26 patients received silicone intubation with MMC

The outcomes were evaluated six months after treatment.

Results

After six months:

  • The success rate for external DCR was 90%
  • The success rate for silicone intubation with MMC was 80.7%

Both treatments showed similar effectiveness, with no significant difference in success rates.

Conclusion

Silicone intubation with MMC is a safe and effective alternative to external DCR. It is less invasive, easier to perform, and takes less time.

Practical Applications

Based on the study, clinics can consider the following:

  • Set clear goals for treatment outcomes.
  • Identify measurable results to track patient progress.
  • Implement AI tools to enhance clinical decision-making.
  • Start with pilot projects to test new methods and monitor their effectiveness.

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