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A Comparative Study of Clinical Outcomes in Locally Advanced Cervical Cancer
Key Findings:
The study compared the outcomes of two treatment approaches for locally advanced cervical cancer in women. It focused on the use of external beam radiation therapy (EBRT) and sequential High Dose Rate Intracavitary Brachytherapy (HDRICBT) with or without concurrent cisplatin administration on the day of intracavitary brachytherapy (ICBT) insertion.
Results:
Both treatment approaches showed similar complete response rates, but a trend emerged during follow-up indicating a possible enhancement in response rates with concurrent cisplatin and ICBT.
Conclusions:
Future studies are recommended to explore the potential benefits of concurrent cisplatin and ICBT further, focusing on optimal drug, dosage, scheduling, and combination with other agents.
Value of Clinical Trials
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