A national multi centre pre-hospital ECPR stepped wedge study; design and rationale of the ON-SCENE study

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The ON-SCENE Study: A Breakthrough in Pre-Hospital Emergency Care

What is the ON-SCENE Study?

The ON-SCENE study is a groundbreaking national multi-centre pre-hospital ECPR (extracorporeal cardiopulmonary resuscitation) stepped wedge study. It aims to evaluate the effectiveness of ECPR in improving survival rates for patients who suffer from cardiac arrest outside of a hospital setting.

The Design and Rationale of the ON-SCENE Study

The study will be conducted in 10 different regions in the Netherlands, with each region participating for a period of 6 months. It involves a total of 250 patients who suffer from cardiac arrest outside of a hospital setting. Half of the patients will receive the current standard of care, while the other half will receive ECPR in addition to the standard care.

The Importance of the ON-SCENE Study

The results of the ON-SCENE study have the potential to significantly impact the way we approach cardiac arrest in the pre-hospital setting. If the study shows that ECPR is effective in improving survival rates, it could lead to a change in protocols and guidelines for emergency medical services (EMS) around the world.

Challenges and Limitations

One of the main challenges is the logistics of implementing ECPR in the pre-hospital setting. Additionally, the study is limited to patients who suffer from cardiac arrest due to a shockable rhythm, which may not be representative of all cases of cardiac arrest.

Conclusion

The ON-SCENE study is a groundbreaking clinical trial that has the potential to change the way we approach cardiac arrest in the pre-hospital setting. By evaluating the effectiveness of ECPR, this study could lead to improved survival rates and better outcomes for patients in critical situations.
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