A safety evaluation of intermittent high-dose inhaled nitric oxide in viral pneumonia due to COVID-19: a randomised clinical study

Safety and Efficacy of High-Dose Inhaled Nitric Oxide for COVID-19 Viral Pneumonia

Key Findings:

• Intermittent 150-ppm iNO-treatment is well-tolerated, safe, and beneficial compared to usual care for spontaneously breathing hospitalised adults diagnosed with COVID-19 viral pneumonia.

• Oxygen support duration was reduced by 2.7 days, a greater number of subjects reached oxygen saturation ≥ 93% within hospitalisation period, and a trend for earlier discharge was demonstrated.

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