Conditions: Hepatocellular Carcinoma
Interventions: Diagnostic Test: ctDNA monitoring; Diagnostic Test: Plasma proteomic analysis
Sponsors: Shanghai Zhongshan Hospital
Not yet recruiting
Biomarkers and Molecular Mechanism Study of Hepatocellular Carcinoma After Radical Resection and Conversion Therapy
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Clinical Research
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Unused potential of lipid-lowering therapy in very high-risk patients with atherosclerotic cardiovascular disease. A retrospective data analysis
“`html Research Summary In a study published in Nutr Metab Cardiovasc Dis, researchers investigated the use of lipid-lowering therapy (LLT) and lifestyle changes in patients with atherosclerotic cardiovascular disease (ASCVD)…
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Autologous mesenchymal stem cells as a component of multidisciplinary rehabilitation of war participants with severe forms of chronic critical lower limb ischemia and pain syndroms
Objective The goal of this study was to evaluate how effective a comprehensive rehabilitation program is for patients with severe leg issues due to combat injuries and chronic critical lower…
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FLOT vs. mDCF: Optimizing Neoadjuvant Chemotherapy for Nonmetastatic Gastric Adenocarcinoma
Understanding the Trial Results This research looked at two cancer treatment plans for patients with nonmetastatic gastric adenocarcinoma, a serious type of stomach cancer. The two plans compared were FLOT…
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Single-centre, randomised and double-blind clinical trial on the efficacy of transcutaneous auricular vagus nerve stimulation in preventing and treating primary headache in children and adolescents: a study protocol
Introduction Primary headaches are a major issue for children and teenagers, showing the need for effective treatments that do not rely on medications. One promising method is called transcutaneous auricular…
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Effectiveness and satisfaction of mindfulness-based cognitive therapy for children on anxiety, depression, and internet addiction in adolescents: Study protocol for a randomized control trial
Understanding the Study on Mindfulness Therapy for Teens This study focuses on adolescents struggling with Internet addiction (IA), who often experience high levels of anxiety and depression. These emotional challenges…
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Clinical and cost-effectiveness of lithium versus quetiapine augmentation for treatment-resistant depression in adults: LQD a pragmatic randomised controlled trial
Clinical Trial Summary: Lithium vs. Quetiapine for Treatment-Resistant Depression Background Treatment-resistant depression (TRD) can be challenging for patients and healthcare providers. Lithium and quetiapine are common medications used to enhance…
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A pilot randomized clinical trial examining the effects of Qigong on inflammatory status and sleep quality in people with Parkinson’s disease
A Pilot Study on Qigong for Parkinson’s Disease Background Neuroinflammation is a key factor in the decline of neurons in people with Parkinson’s disease (PD). High levels of inflammatory markers,…
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Prefrontal Transcranial Direct Current Stimulation in Pediatric Attention-Deficit/Hyperactivity Disorder: A Randomized Clinical Trial
Understanding Transcranial Direct Current Stimulation for ADHD What is the Study About? This study looks at a new treatment called transcranial direct current stimulation (tDCS) for children with attention-deficit/hyperactivity disorder…
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Check your snoring risk: AI bot evaluates if it’s harmless or sleep apnea
How the Snoring Risk Chatbot Works Snoring affects nearly half of adults occasionally, but when it’s paired with symptoms like gasping or excessive daytime fatigue, it might signal obstructive sleep…
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Conventional colonoscopy vs. cap-assisted colonoscopy: there are differences in colonoscopy performance?
Conventional Colonoscopy vs. Cap-Assisted Colonoscopy Introduction Colonoscopy is the main method for diagnosing colorectal cancer. However, the results for detecting polyps and adenomas have varied with different devices. Objectives This…
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Comparing performance of primary care clinicians in the interpretation of SPIROmetry with or without Artificial Intelligence Decision support software (SPIRO-AID): a protocol for a randomised controlled trial
Comparing Performance of Primary Care Clinicians in the Interpretation of SPIROmetry with or without Artificial Intelligence Decision Support Software (SPIRO-AID): A Protocol for a Randomised Controlled Trial ABSTRACT Spirometry, a…
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A Web-Based Tool to Perform a Values Clarification for Stroke Prevention in Patients With Atrial Fibrillation: Design and Preliminary Testing Study
Atrial Fibrillation and Stroke Prevention Background Atrial fibrillation (AF) increases the risk of stroke. Anticoagulation medications (OAC) help prevent strokes but may also cause bleeding. Current guidelines don’t clearly suggest…
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Optimal Needle Choice for Ultrasound-Guided Pleural Biopsy: Insights for Healthcare Professionals
Understanding the Study on Pleural Needle Biopsies What Was the Study About? This study looked at two types of needles used in ultrasound-guided pleural needle biopsies. These biopsies help doctors…
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Comparative Study: Topical Caspofungin vs. Voriconazole for Fungal Keratitis Treatment
Understanding the Trial Results This study looked at two treatments for fungal keratitis, an eye infection caused by fungi. The treatments compared were: Topical caspofungin 0.5% Topical voriconazole 1% What…
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Risk expression using likelihood ratios and natural frequencies in Bayesian inference tasks-a preregistered randomized-controlled crossover trial
Understanding Diagnostic Tests for Better Healthcare Background Medical students need to learn how to read diagnostic tests well to make smart medical decisions in the future. Natural frequencies help understand…
