Blood pressure changes in patients after Minoxidil microinfusion to treat female pattern alopecia: analysis of a randomized, single blinded, placebo controlled clinical trial

Background

Microinfusion is a skin treatment that uses tiny needles to deliver medications directly into the skin. One common medication used in this way is minoxidil, which helps with hair loss. However, there is limited information on how this method affects the body, particularly blood pressure.

Objective

The aim of this study was to measure blood pressure changes before and after applying minoxidil to the scalp using microinfusion. This helps us understand if the medication has any effects on the body beyond the scalp.

Methods

This study involved 24 participants who were randomly divided into two groups: one group received minoxidil, while the other received a saline solution (placebo). Each participant had three treatment sessions over three months, and their blood pressure was measured before and after each session.

Results

Participants who received minoxidil showed a significant decrease in diastolic blood pressure after treatment. In contrast, those in the placebo group experienced a notable increase in systolic blood pressure, likely due to discomfort during the procedure.

Conclusion

The findings indicate that minoxidil can be absorbed into the bloodstream when delivered through microinfusion, leading to a decrease in diastolic blood pressure. This suggests that while treating hair loss, minoxidil may also have systemic effects.

Opportunities for Clinics and Patients

Based on the trial data, clinics can:

Set clear goals for monitoring blood pressure changes in patients receiving minoxidil microinfusion.
Utilize AI tools to track patient outcomes and optimize treatment plans.
Implement pilot projects to assess the real-world impact of these treatments.