Clinical trials

Understanding the Trial Results What Worked? The “Wrapped” program, which helps young people learn to use condoms correctly, showed promise in encouraging safer sex practices. 75.7% of participants returned valid chlamydia self-samples after 12 months, indicating they were engaged and following through with testing. What Didn’t Work? Recruitment was low, with only 1.5% of the […] ➡️➡️➡️

Understanding the Study Results This study looked at how well dressings that contain chlorhexidine-gluconate (CHX) work to prevent infections in patients with external ventricular drains (EVDs). These drains help manage fluid in the brain and can sometimes lead to infections called EVD-associated infections (EVDAIs). What Worked? Using CHX dressings significantly reduced the rate of infections: […] ➡️➡️➡️

Understanding the BEST Trial Results What is the BEST Trial? The BEST trial looked at how well a digital health app called Kranus Lutera helps men with lower urinary tract symptoms (LUTS). LUTS can include problems like needing to urinate often or urgently. This trial involved 237 men who were divided into two groups: one […] ➡️➡️➡️

Understanding the Study Results The MTN-042/DELIVER study looked at how safe two methods of preventing HIV are for pregnant women and their babies. The two methods tested were: Dapivirine Vaginal Ring (DVR): A ring placed inside the vagina that releases medicine to prevent HIV. Oral PrEP: A daily pill that contains two medicines (tenofovir and […] ➡️➡️➡️

Understanding the Trial Results The research looked at people with systemic lupus erythematosus (SLE), a condition where the body’s immune system attacks its own tissues. The aim was to see how these patients were doing in terms of their quality of life (HRQoL) even when their disease was controlled (in a state called LLDAS or […] ➡️➡️➡️

Understanding the Study This study looked at how using WhatsApp for education could improve women’s beliefs about mammograms, their confidence in getting tested, and their actual behavior regarding regular mammograms. What Happened in the Study? 1. Participants: 81 women aged 40-69 took part. They were divided into two groups: one group received training through WhatsApp, […] ➡️➡️➡️

Understanding the Study and Its Results This study looked at a new app called PrEPresent, designed to help young people from diverse backgrounds learn about and access Pre-exposure Prophylaxis (PrEP), a medication that can prevent HIV. The researchers wanted to see if this app would be effective and if people would accept using it. What […] ➡️➡️➡️

Understanding the Study Results This study looked at the health effects of eating fresh-cut fruits sold by street vendors in Bangladesh. It involved 300 people who were divided into two groups: one group ate the fruits, and the other group did not. The results showed that those who ate the fruits had more stomach problems […] ➡️➡️➡️

Understanding the Trial Results This research looked at patients with gastric cancer receiving neoadjuvant chemotherapy (NAC). This type of chemotherapy is given before surgery. The study found that many patients lost important body tissues during this treatment, which can impact survival rates. What Worked? Identifying that losing significant amounts of adipose tissue (fat) during NAC […] ➡️➡️➡️

Understanding the Trial Results This study looked at how well an electronic balance aid works when combined with medication for patients with sudden balance issues due to inner ear problems. The results showed that using this device along with medication helped patients feel better and improve their balance more than medication alone. What Worked? The […] ➡️➡️➡️

Understanding the CYCLONE 2 Trial Results What Was the Trial About? The CYCLONE 2 trial looked at a new treatment for men with advanced prostate cancer that does not respond to hormone therapy. The treatment combined two drugs: abemaciclib and abiraterone. The goal was to see if this combination could help patients live longer without […] ➡️➡️➡️

Trial Overview The TUXEDO-3 trial tested a new treatment called Patritumab deruxtecan (HER3-DXd) for patients with breast cancer that has spread to the brain. This treatment targets a specific protein (HER3) found in many brain metastases. The main goal was to see if this drug could help patients whose brain cancer is getting worse after […] ➡️➡️➡️

Understanding the TUXEDO-3 Trial Results The TUXEDO-3 trial studied a new treatment called Patritumab deruxtecan (HER3-DXd) for patients with advanced non-small-cell lung cancer (NSCLC) who also have brain metastases. This means the cancer has spread to the brain. Here’s what the results mean for patients and clinics. What Worked? Out of 20 patients, 6 (30%) […] ➡️➡️➡️

Understanding the Trial Results This study looked at how the order of using two questionnaires, the Multidimensional Dyspnoea Profile (MDP) and the Dyspnoea-12 (D12), affects the responses about breathlessness in patients with heart and lung diseases. What Worked? The order of completing the questionnaires (MDP first or D12 first) did not significantly change the results. […] ➡️➡️➡️

Understanding the Trial Results This trial compared two types of online therapy for depression: Message-Based Psychotherapy (MBP) and Video-Based Psychotherapy (VBP). Here’s what we learned: What Worked? Both MBP and VBP were effective for treating depression, with no major differences in how much they helped participants. MBP had fewer participants dropping out of treatment compared […] ➡️➡️➡️

Understanding the Study on Astaxanthin for Heart Failure What is Astaxanthin? Astaxanthin is a natural antioxidant found in certain foods, like salmon and shrimp. It helps protect our cells from damage caused by harmful molecules called free radicals. Why is this Study Important? Chronic heart failure (HF) can lead to serious health problems. This study […] ➡️➡️➡️

Understanding the Study on ADHD Intervention What Was the Study About? This study looked at a new way to help adults with Attention-Deficit/Hyperactivity Disorder (ADHD) using a method called Self-Determination Theory (SDT). Instead of focusing only on what people with ADHD struggle with, this approach aims to improve their overall quality of life and personal […] ➡️➡️➡️

Understanding the Trial Results This study looked at how to encourage Vietnamese Americans aged 50 and older to get screened for colorectal cancer (CRC). The screening method used was the fecal immunochemical test (FIT), which is a simple, non-invasive test that checks for signs of cancer in stool samples. What Worked? The special program helped […] ➡️➡️➡️

Understanding the Salmonella Paratyphi A Vaccine Trial Results What is Salmonella Paratyphi A? Salmonella Paratyphi A is a type of bacteria that causes enteric fever, affecting over 2 million people each year. Currently, there is no approved vaccine to prevent this illness. What Did the Trial Study? This study tested a new vaccine called CVD […] ➡️➡️➡️

Understanding the European Study of Prostate Cancer Screening What Was the Study About? The European Randomized Study of Screening for Prostate Cancer (ERSPC) started in 1993 to see if testing for prostate cancer using a blood test called PSA (prostate-specific antigen) could reduce deaths from this disease. As more people live longer, it’s important to […] ➡️➡️➡️