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Comparison of novel PSMA-targeting [177Lu]Lu-P17-087 with its albumin binding derivative [177Lu]Lu-P17-088 in metastatic castration-resistant prostate cancer patients: a first-in-human study
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Clinical Research
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Direct-Access Physiotherapy: Enhancing Pediatric Emergency Care for Musculoskeletal Issues
Objective of the Study This study looked at whether allowing children and teens to see a physiotherapist directly in the emergency department (ED) for muscle and bone issues would be…
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Regression and growth rates in androgen deprivation therapy for advanced castration-sensitive prostate cancer
Research Overview This study focuses on comparing cancer regression (d) and growth (g) rates in patients with advanced castration-sensitive prostate cancer (CSPC) undergoing androgen deprivation therapy (ADT). Purpose The goal…
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Effect of integrating traditional and modern healthcare systems on tuberculosis case detection in Ethiopia: a cluster randomized controlled study
Background Detecting tuberculosis (TB) cases is crucial for controlling the disease, especially in countries like Ethiopia where TB is common. This study looked at combining traditional and modern TB care…
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Efficacy of Lactobacillus reuteri and Racecadotril in Treating Pediatric Rotavirus Enteritis
Understanding the Study on Lactobacillus reuteri and Racecadotril This study looked at how well combining two treatments, Lactobacillus reuteri and racecadotril, works for children with rotavirus enteritis, a common intestinal…
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Comparing Platelet-Rich Plasma and Nerve Ablation for Knee Osteoarthritis Pain Relief
Understanding the Trial Results This clinical trial compared two treatments for knee osteoarthritis: platelet-rich plasma (PRP) injections and radiofrequency ablation of genicular nerves (GNRFA). The findings help us see what…
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Effectiveness of newborn infant parasympathetic evaluation (NIPE) index for guiding intraoperative fentanyl administration in children under 2 years: a randomized controlled trial
Effectiveness of NIPE Index for Pain Management in Young Children Background Assessing pain in infants is difficult because they cannot express themselves verbally. Current methods rely on observing behavior, which…
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Is Mat pilates effective in lower limb strength and hand grip strength of people with Parkinson’s? A randomized clinical trial with follow-up
Is Mat Pilates Effective for People with Parkinson’s? Study Overview This study investigates whether Mat Pilates can improve lower limb strength and hand grip strength in individuals with Parkinson’s disease.…
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Cost-effectiveness of talazoparib for patients with germline BRCA1/2 mutated HER2-negative advanced breast cancer in China and the US
Cost-effectiveness of Talazoparib for Advanced Breast Cancer Key Findings: Talazoparib, a targeted PARP inhibitor, has shown significant extension in progression-free survival and improved response markers for patients with germline BRCA1/2…
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Effectiveness of bilateral tongue base mucosectomy by transoral robotic surgery or transoral laser microsurgery in combination with tonsillectomy in identifying head and neck primary cancer of unknown primary: a randomized phase 2 protocol (RoboCUP trial)
“`html Background In patients with swollen lymph nodes in the head and neck area, finding the original tumor site helps doctors target radiotherapy more accurately. This can lead to better…
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Phase II Study of Defactinib (VS6063) in Patients With Tumors With NF2 Loss: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol U
Phase II Study of Defactinib (VS6063) in Patients With Tumors With NF2 Loss Overview of the Study The NCI-MATCH trial focused on patients with various cancers, assigning them targeted therapies…
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Supervised vs. Home-Based Exercise: Which is Better After PRP Injections for Knee Osteoarthritis?
Understanding the Research on Knee Osteoarthritis This research compares two types of exercise programs for patients with knee osteoarthritis (OA) after receiving platelet-rich plasma (PRP) injections. Here’s what you need…
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Comparison of intramyocellular lipid metabolism in patients with diabetes and male athletes
Study Title: Comparison of Intramyocellular Lipid Metabolism Published in: Nat Commun. 2024 May 15;15(1):3690 Summary: The study compared intramyocellular lipid metabolism in male endurance athletes and patients with type 2…
