Comparison of the pleiotropic effect of atorvastatin and rosuvastatin on postmenopausal changes in bone turnover: A randomized comparative study

Comparison of Atorvastatin and Rosuvastatin Effects on Bone Turnover in Postmenopausal Women

Key Findings:

• Statins, commonly used for dyslipidemia, may have additional benefits on bone health.

• This study compared the impact of atorvastatin and rosuvastatin on bone turnover in postmenopausal women.

• After 12 months, atorvastatin showed potential superiority in inhibiting adverse changes in bone turnover compared to rosuvastatin.

Practical Implications:

• Choosing atorvastatin over rosuvastatin in early postmenopausal women may help reduce the risk of osteoporosis and subsequent fractures.

• Further research involving a larger population is needed to confirm these findings and their clinical applications.

Value of Clinical Trials

Clinical trials are essential for developing safe and effective treatments, and it’s crucial to translate their benefits into everyday medical practice.

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