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Correlation between dexmedetomidine and postoperative sleep quality in older patients undergoing intestinal surgery

Objective

This study looked at how dexmedetomidine affects sleep quality after intestinal surgery in older patients.

Methods

We studied 112 older patients, dividing them into two groups. One group received saline (Group A), and the other received dexmedetomidine (Group B). We measured sleep quality before surgery and on days 1, 3, 7, and 30 after surgery using the Pittsburgh Sleep Quality Index (PSQI). We also checked urinary melatonin and cortisol levels and assessed pain using the Visual Analogue Scale (VAS).

Results

After surgery, both groups had higher PSQI scores, indicating poorer sleep. However, Group B (dexmedetomidine) had lower scores and fewer sleep issues on days 1 and 3 compared to Group A. Group A had lower melatonin levels and higher cortisol levels, along with more pain. Overall, patients who did not receive dexmedetomidine experienced more sleep problems. Factors like dexmedetomidine dosage, gender, and pain levels significantly influenced sleep quality.

Conclusions

Using dexmedetomidine improves sleep quality in older patients after intestinal surgery by lowering cortisol, increasing melatonin, and reducing pain, leading to better recovery outcomes.

Opportunities for Improvement

Based on the trial data, clinics can set clear goals to enhance postoperative care:

  • Monitor sleep quality using PSQI.
  • Evaluate cortisol and melatonin levels in patients.
  • Focus on pain management strategies.

AI Tools for Clinical Needs

Select AI solutions that address specific tasks related to monitoring and improving patient outcomes based on this study.

Implementation Steps

Start with a pilot project to track the effectiveness of dexmedetomidine in improving sleep quality and recovery in older patients after surgery.

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