Effect of 7-day dietary supplementation with grape seed extract on cardiac autonomic and hemodynamic responses in elevated and stage 1 hypertension

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Study Overview

This study examined how a 7-day dietary supplement of grape seed extract (GSE) affects heart function and blood pressure in men with elevated and stage 1 hypertension.

Key Findings

  • GSE supplementation led to a decrease in resting diastolic blood pressure (DBP) and mean arterial pressure (MAP).
  • No significant changes were observed in heart rate, stroke volume, cardiac output, systolic blood pressure, or heart rate variability between GSE and placebo treatments.
  • GSE may help lower blood pressure through relaxation of blood vessels.

Practical Healthcare Results

Grape seed extract can be a beneficial addition to dietary plans for individuals with elevated blood pressure, potentially reducing the risk of developing more serious hypertension.

Measurable Outcomes

Clinics can aim for the following goals:

  • Reduction in diastolic blood pressure among patients taking GSE.
  • Improvement in overall cardiovascular health without adverse effects on heart rate or other hemodynamic measures.

Next Steps for Clinics

To implement GSE supplementation effectively:

  1. Start with a pilot project to assess the effects of GSE on a small group of patients.
  2. Track results using appropriate AI tools to analyze data and monitor outcomes.
  3. Expand the project based on initial findings to include more patients and refine treatment protocols.

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