Effect of l-arginine on Sexual Function in Women with Depression
Background
Research suggests that l-arginine may improve sexual function and alleviate depression, but its effects on women with depression have not been studied concurrently.
Methods
Women diagnosed with major depressive disorder were enrolled in a triple-blind clinical trial. They were divided into two groups: one received l-arginine and the other received a placebo for four weeks. Their depression severity and sexual function were evaluated at baseline, after four and eight weeks.
Results
All patients showed a decrease in depression severity. The group receiving l-arginine showed improvement in sexual function, particularly in lubrication and orgasm, with minimal side effects observed.
Conclusion
L-arginine supplementation can improve sexual function and mood in women with depression. Further research is needed to validate these results with higher dosages and larger populations.
Trial Registration
Iranian Registry of Clinical Trial: IRCT20100127003210N26
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